Depo-Provera injection and negative mood

How our community feel depo-Provera injection has affected their moods and emotions

Data is taken from self reported Lowdown user reviews

No change

28%

Don't know

7%

Out of the 197 reviews for depo-Provera injection, 110 people (56%) reported negative mood.

Reviewers that reported negative mood as a side effect

Data is taken from self reported Lowdown user reviews

Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  4 days ago

I got with a new partner a few years back and gave this ago as I wanted something I didn’t need to remember to take. I gained weight fast, I had mood changes, my skin broke out badly, my periods were heavier than before. I only ever had one injection then stopped as I no longer needed it and I didn’t like how it made me feel. Unfortunately I had a rare side effect where it stopped my periods/ovulation all together for 12 months I was referred to gynaecology at 6 months and luckily after all the scans everything was normal and by month 12 my cycle returned without needing to be medically induced. This is not a horror story but important that you could react the same or if you are reacting the same please get referred to gynaecology and hopefully your periods will return 🤍

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Somewhat negative mood

2 more effects

0 helpful

0 comments

Used for 1 - 3 mo
20 years old
🇬🇧 UK
  •  3rd Apr 26

This has made my sex life a living hell .I get scared to have sex with my partner since I associate the vaginal dryness with this Depo shot ,the sex is always pain towards the end as there’s not enough lubrication


Very negative mood

2 more effects

0 helpful

0 comments

Used for 3 - 6 mo
28 years old
🇬🇧 UK
  •  6th Oct 25

Worst experience I’ve ever had. Since taking this I’ve felt constantly irritated, had complete lack of concentration and it’s completely wiped out my sex drive. I have now been bleeding for 2 months with no break. I have never regretted taking something so much it’s honestly made me miserable.


Very negative mood

1 more effect

0 helpful

0 comments

Depo-Provera injection common side effects

Data is taken from self reported Lowdown user reviews

41% of depo-Provera injection reviewers reported vaginal dryness

39% of depo-Provera injection reviewers reported tender breasts

34% of depo-Provera injection reviewers reported vaginal discharge

30% of depo-Provera injection reviewers reported lower back pain

29% of depo-Provera injection reviewers reported sweating more than usual


Possible depo-Provera injection side effects

Data is taken from self reported Lowdown user reviews

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