Side effects
Depo-Provera injection common side effects
Data is taken from self reported Lowdown user reviews
41% of Depo-Provera injection reviewers reported vaginal dryness
41% of Depo-Provera injection reviewers reported tender breasts
34% of Depo-Provera injection reviewers reported vaginal discharge
31% of Depo-Provera injection reviewers reported lower back pain
29% of Depo-Provera injection reviewers reported period like cramps
Depo-Provera injection rare side effects
Data is taken from self reported Lowdown user reviews
4% of Depo-Provera injection reviewers reported a latex allergy
4% of Depo-Provera injection reviewers reported pelvic infection
3% of Depo-Provera injection reviewers reported discomfort wearing contact lenses
Possible Depo-Provera injection side effects
Data is taken from self reported Lowdown user reviews
- Vaginal dryness (41%)
- Tender breasts (41%)
- Vaginal discharge (34%)
- Lower back pain (31%)
- Period like cramps (29%)
- Sweating more than usual (28%)
- Breast enlargement (27%)
- Headaches (26%)
- Nausea or vomiting (22%)
- Thrush (18%)
- Body hair increase (16%)
- Migraines (12%)
- Dizziness (11%)
- Cystitis (11%)
- Body hair getting darker (9%)
- High blood pressure (9%)
- Migraine with aura (7%)
- Hair loss (5%)
- A latex allergy (4%)
- Pelvic infection (4%)
- Discomfort wearing contact lenses (3%)
Reviews
3.0
185 reviews
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Community reviews
Used for 18 mo - 3 yr
28 years old
🇬🇧 UK
• 2 weeks ago
I’ve had a really positive experience with depo. I was on it for around 4 years pre-covid, and have currently been using again for 18 months. Periods have completely stopped and I haven’t experienced side effects (my hair might be slightly thinner, but I’m not sure if I’d just never noticed I have thin hair). After stopping use the first time it did take many months for my periods to return. I’m only thinking about stopping taking it now with the recent studies on links to brain tumours.
Top side effects not reported
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Used for 18 mo - 3 yr
25 years old
🇬🇧 UK
• 2 weeks ago
I have really enjoyed not having periods and not having to remember my pill as I am very forgetful. I have gained an increased sex drive and I used to get cramps all the time and it stopped most of those. I rarely get migraines. Maybe one every two months. My only major issue was my hair loss. I’ve lost about 50% of my hair and now it’s brittle but after taking calcium supplements and changing my diet it’s a bit more normal. It could be unrelated but around the same time as I started the depo I also got Dyshidrotic eczema on my feet. What makes me think this could be related is I’m also very itchy on my hands, and legs since starting. I could just be getting older and I’ve had issues in the past with my hips but I’ve also pulled my back, and badly sprained my ankle and hip. This has only happened after starting the depo. After a year of being on it everything seems to have leveled out. All bad points above have now become less noticeable and I feel very comfortable. External issues are still an issue like being constantly interrogated like I don’t know what I’m doing in the nurses office as I take my depo every 10 weeks due to bleeding for the last 3 weeks of the cycle. They also seem to want you on the coil I’m not sure what that is about but it’s very annoying. Also depending on who is administering the shot you may feel basically no pain or a ton that could last for a few hours These side effects may not be for some but from my past personal issues I am happy with the contraceptive compared to others I’ve tried
Improved skin
1 more effect
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Used for 12 - 18 mo
18 years old
🇬🇧 UK
• 11th Sep 24
I went on thsi injection due to my terrible experience with rigevidon, at first everything was fine as my skin cleared up, i only get the odd spot which is supported by acne medication- which was great considering i am acne prone. However it was beginning clear that i was gaining weight, I started off as a size 8 (very slim and petite) to currently being a size 14, leading to a size 16. My hips have also widened, this has led to an increase of SO many stretch marks, it has had an affect on my confidence due to this durastic change, while having the same diet the whole time. Yet this may be because i began at 16 now 18, coming into adulthood maybe?? At the minute my moods are terrible, i am very irritable, riddled with anxiety and more sensitive; so if youre looking into this as someone who has suffers with mental health I would not recommend. The pain of the injection is not bad however I am attempting to come off of this contracpetive as soon as possible yet just struggling which pill to choose due to my fear of weight gain, poor skin and loosing my sex drive. Just remember eveyones experience is different this is just mine :)
Somewhat negative mood
2 more effects
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Used for 1 - 3 mo
32 years old
🇬🇧 UK
• 28th Aug 24
I would absolutely never recommend this to anyone. As someone who has previously struggled with mental health issues but has been well for about 10 years, my mood has been incredibly low and my anxiety through the roof. This is not something I’ve experienced for years (actually last time I was on hormonal contraception). I feel very lucky to be in touch with my moods and still having therapy so I’ve been able to quickly be aware this is likely to be the Depo as nothing else has changed to bring this on. I will not be using this again and would really recommend others proceed with caution.
Very negative mood
2 more effects
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Used for 1 - 3 mo
22 years old
🇬🇧 UK
• 24th Aug 24
I went on the depo injection after having my little boy as I thought it was an easy form of contraceptive as I didn’t have to remember to take it everyday. Fast forward a week post injection I started with the most horrific nausea, stomach pains, back pain and anxiety. I thought I maybe have a bug so went to the doctor who ran some bloods (all came back clean) never felt anxious or sick prior to having the injection so the only thing I can think of that is new is the depo. I have now been nauseas well over a month every single day to the point I am on anti - sickness tablets. I will not be having it again as it changes your body and emotions so much and the other downside there is no reversal so once it’s in if you suffer from the side effects you have to basically put up with it until it’s up for renewal. Wish I had done my research before as I have read on numerous sites that the hormone levels they give are so high and this is what causes all the adverse effects.
Very negative mood
1 more effect
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Used for 3 - 6 mo
18 years old
🇬🇧 UK
• 11th Aug 24
Being on the injection has changed my life. After years of misery I finally feel like myself again. My mood has almost completely stabilised and my mental health has never been better. Physically my body has found it great too, I no longer find myself exhausted from heavy periods and my boobs have even gotten abit bigger which has been a big plus. I feel like a person again after going on the injection, After years of my hormones controlling my life I no longer feel crazy, I have control of my life again.
Very positive mood
1 more effect
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Used for 3 - 6 mo
37 years old
🇬🇧 UK
• 8th Aug 24
Probably the worst method of hormonal contraception I’ve used. In terms of side effects (which the doctors did not discuss with me) there were Night sweats, loss of sex drive, terrible mood swings and Vaginal dryness to name just a few. Yes it did the job it was meant to, but the side effects were enough for me to make the decision to move off hormonal contraceptives altogether now.
Very negative mood
2 more effects
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Used for 5 - 8 yr
34 years old
🇬🇧 UK
• 15th Jul 24
Stopped my periods completely which was great, but was depressed the entire time I was on it (and didn't realise why until I came off) also had zero sex drive until I came off it.
Very negative mood
1 more effect
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Used for 6 - 12 mo
31 years old
🇬🇧 UK
• 22nd May 24
I was not offered an alternative injection and was adbised against it as i already was dinosed with depression.its been very difficult trying to feel normal and have a great s** life. I am already a mother and would like to wait a while before or IF i do have any more children. This contraception is extemly strong, i noticed many changes to my body. From the frist day i took the injection. It is brilliant at stopping me from getting pregnnt again though.
Somewhat negative mood
2 more effects
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Used for 12 - 18 mo
25 years old
🇬🇧 UK
• 21st May 24
I was placed on the Depo injections back in 2019 and had a total of 5/6 injections. They were stopped because they caused severe anxiety, multiple panic attacks daily and severe depression. The GP deemed it unsafe for me to continue as the mental health side effects were incredibly awful.
Very negative mood
1 more effect
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