Depo-Provera injection and irregular periods

How our community feel depo-Provera injection has affected their periods

Data is taken from self reported Lowdown user reviews

Stopped

70%

No change

2%

Don't know

1%

Out of the 199 reviews for depo-Provera injection, 25 people (13%) reported irregular periods.

Reviewers that reported irregular periods as a side effect

Data is taken from self reported Lowdown user reviews

Used for 1 - 3 mo
27 years old
🇬🇧 UK
  •  today

First 3 weeks were fine, I spent first 3 days filled with rage and nausea and a few headaches but fine. First expected period rolled around at 3 weeks in and didn't stop, like at all (day 77 as I write this). About 6 weeks in my mood crashed. As someone who has previously had mental health problems, I was incredibly apprehensive about going on any kind of hormonal birth control because I was scared of side effects. But in order to get my tubes tied, my doctors wanted to see me try this first and everyone reassured me that I was just being paranoid and it wouldn't be as bad as I imagined. Unfortunately it was worse than I imagined. I spent 4 weeks getting progressively more suicidal until I finally went to the doctors (which was its own story) but had to take three Valium a day in order to function and go to work. At the time of writing, I'm 2 weeks out of the 12-week expected window, still bleeding and still suffering mentally but less so and more manageably. This experience has put me off trying any other form of birth control. I had done this to try and reduce PMS symptoms and wish I never had. I was also recommended the mirena coil but didn't like the idea of having to have it inserted or removed if things went wrong/justify myself to a doctor

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Very negative mood

1 more effect

0 helpful

0 comments

Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  5th May 26

I got with a new partner a few years back and gave this ago as I wanted something I didn’t need to remember to take. I gained weight fast, I had mood changes, my skin broke out badly, my periods were heavier than before. I only ever had one injection then stopped as I no longer needed it and I didn’t like how it made me feel. Unfortunately I had a rare side effect where it stopped my periods/ovulation all together for 12 months I was referred to gynaecology at 6 months and luckily after all the scans everything was normal and by month 12 my cycle returned without needing to be medically induced. This is not a horror story but important that you could react the same or if you are reacting the same please get referred to gynaecology and hopefully your periods will return 🤍


Somewhat negative mood

2 more effects

0 helpful

0 comments

Used for 1 - 3 mo
27 years old
🇬🇧 UK
  •  26th Jun 25

Things I’ve had history struggling with in the past: depression, anxiety, weight Things depo increased: depression, anxiety, weight


Very negative mood

1 more effect

0 helpful

0 comments

Depo-Provera injection common side effects

Data is taken from self reported Lowdown user reviews

41% of depo-Provera injection reviewers reported vaginal dryness

39% of depo-Provera injection reviewers reported tender breasts

34% of depo-Provera injection reviewers reported vaginal discharge

30% of depo-Provera injection reviewers reported lower back pain

29% of depo-Provera injection reviewers reported period like cramps


Possible depo-Provera injection side effects

Data is taken from self reported Lowdown user reviews

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