Depo-Provera injection and acne
How our community feel depo-Provera injection has affected their skin
Data is taken from self reported Lowdown user reviews
No change
18%
Don't know
5%
Out of the 197 reviews for depo-Provera injection, 11 people (6%) reported acne.
Reviewers that reported acne as a side effect
Data is taken from self reported Lowdown user reviews
Used for 1 - 3 mo
29 years old
🇬🇧 UK
• 5 days ago
I got with a new partner a few years back and gave this ago as I wanted something I didn’t need to remember to take. I gained weight fast, I had mood changes, my skin broke out badly, my periods were heavier than before. I only ever had one injection then stopped as I no longer needed it and I didn’t like how it made me feel. Unfortunately I had a rare side effect where it stopped my periods/ovulation all together for 12 months I was referred to gynaecology at 6 months and luckily after all the scans everything was normal and by month 12 my cycle returned without needing to be medically induced. This is not a horror story but important that you could react the same or if you are reacting the same please get referred to gynaecology and hopefully your periods will return 🤍
Somewhat negative mood
2 more effects
0 helpful
0 comments
Used for 1 - 3 mo
34 years old
🇬🇧 UK
• 6th Jul 25
All women should really do the research before starting this medication. I have read quite a few stories online of women who have felt the same. I have basically felt like a completely different person. I am near on the end of one injection and I will not be going back for another. It’s absolutely ruined my relationship with my partner. I’ve been absolutely horrible to him and it’s only now I’m starting to realise just what this injection did to me. Thank goodness he’s so understanding and helped me through it because I was literally horrendous. Literally a few days after I had it I was a different person, I hated him. Everything he done annoyed me, I was rude and hurtful and I couldn’t control it. I would snap in and out of moods so badly that we named the other “person” Patrica. He was constantly walking on egg shells as he never knew which version he would get. I am so upset that I have felt this way in the last few months. So much so I was having suicidal thoughts. I pray that anyone doesn’t risk it because it’s been 3 months of hell for us.
Very negative mood
2 more effects
0 helpful
0 comments
Used for 1 - 3 mo
16 years old
🇬🇧 UK
• 21st Mar 25
This is pretty good for preventing pregnancy and my periods are thankfully gone, but now I have acne after having years of clear skin. It’s hormonal acne too due to the progesterone in the injection, so a nightmare to get rid of. I was prewarned about this issue but still hate it. I feel like my mood has gone lower too and I am more irritable than usual. Unsure whether I’ll get it again I will probably go back to the Lucette pill as that completely cleared my skin.
Somewhat negative mood
1 more effect
0 helpful
0 comments
Depo-Provera injection common side effects
Data is taken from self reported Lowdown user reviews
41% of depo-Provera injection reviewers reported vaginal dryness
39% of depo-Provera injection reviewers reported tender breasts
34% of depo-Provera injection reviewers reported vaginal discharge
30% of depo-Provera injection reviewers reported lower back pain
29% of depo-Provera injection reviewers reported sweating more than usual
