Side effects

Desogestrel pill side effects

2.7

401 reviews

What Lowdown reviewers say

Data is taken from self reported Lowdown user reviews

33% somewhat negative

43% stopped periods

52% lost sex drive

44% no impact

47% no impact on skin

Cycle return

41% don’t know impact

Desogestrel pill

Desogestrel pill common side effects

Data is taken from self reported Lowdown user reviews

52% of Desogestrel pill reviewers reported tender breasts

45% of Desogestrel pill reviewers reported period like cramps

42% of Desogestrel pill reviewers reported breast enlargement

41% of Desogestrel pill reviewers reported vaginal discharge

37% of Desogestrel pill reviewers reported vaginal dryness


Data is taken from self reported Lowdown user reviews


Reviews

2.7

401 reviews

Filter reviews

Community reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
24 years old
🇬🇧 UK
  •  today

Desogestrel pill  

Since i was 18 i tried 7 different contraception methods (pills and nuvaring). However i had diagnosed migraines, but none of the OBGYNs i was seeing though this was a concern. Now i am 24 and i finally found a competent OBGYN thanks to my friend. She was the only one who really looked through and studied my medical history and suggested taking desogestrel for my ovarian cysts and corpus luteum cyst, which were more rare occasion. I started my second pack today and i’m scared to jinx but the last two weeks were amazing. The first two weeks were a hell, i had bleeding for quite some time and then spotting for a week or more. Now i don’t have any spotting, my sex drive is the same, i am happy and i feel like i even started to lose weight. I am planning to update my story next month to see how my body would feel on these pills.

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Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
30 years old
🇬🇧 UK
  •  3 weeks ago

Desogestrel pill  

It feels nice not having a period. But I’ve noticed I’ve become more spotty , I sweat more also & get thrush


Somewhat positive mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
21 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

I spotted for 3 months straight, but then stopped periods all together. I felt a bit sick after taking it, so i should’ve probably taken it after food or at night but i took in the morning. I feel like it made me quite anxious, but i’ve been off it for two years and still have anxiety problems so i’m not 100% whether it’s related! The sickness feeling made me feel quite nervous i think. No other side effects.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
20 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

Ok but not a fan of the hair loss and continuous spotting


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

i’m not sure if it is normal but i have been on this pill for 3 months. a week into the taking the pill my period finally came back after around 100 days. since then ive had very irregular periods often bleeding for extended periods of time and also spotting more often with the periods being closer together. i have also experienced much more mood changes as i have felt somewhat more depressed on this pill. this might just be my experience and might also be influenced by the fact i am still going through pubity as i’m 16 yet i still can’t stop thinking that something is wrong .


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
24 years old
🇬🇧 UK
  •  23rd Jul 25

Desogestrel pill  

I’m was happy with the mini pill as I took it while breastfeeding my son, however as soon as I weaned him my periods came back but they were all over the place. I bled for nearly 2 weeks straight then it finally stopped, but only for 3 days then it started again. If it wasn’t for this issue I’d have kept using the mini pill but I couldn’t deal with it anymore as it was preventing me from living my life normally


Somewhat positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  10th Jul 25

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  5th Jul 25

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
21 years old
🇬🇧 UK
  •  26th Jun 25

Desogestrel pill  

The first 3-5 months were a bit rough, having sex would cause me to get a period and sometimes was painful. I also was definitely more emotional than before. It all calms down over time, I’ve been on it for almost 3 years now and it was the best decision i get very occasionally spotting and cramps if i miss a pill or two but overall I like it


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  24th Jun 25

Desogestrel pill  

I was on Microgynon 30 for almost 8 years and I never had any issues! I changed 3 months ago to the progesterone only pill (Desogesterel) due to my friend getting a blood clot from microgynon, and within a month I began getting spots all over my jawline! I have now had constant spots for 2 months. I also have breakthrough bleeding which I never had on Microgynon. I will be heading back to the pharmacy to discuss my options


Worse skin

0 helpful

0 comments

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