Slynd pill vs Desogestrel pill
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Overview
Rated 3.5
21 reviews
Daily
Frequency
93% - 99+%
Effectiveness
None
Blood clot risk
None
Effect on fertility
Rated 2.7
386 reviews
Daily
Frequency
91% - 99+%
Effectiveness
None
Blood clot risk
None
Effect on fertility
What Lowdown reviewers say
Benefits: What this contraceptive can help with
There are no benefits that are recognised in scientific research or guidelines for this contraceptive
Period pain
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Check out our latest reviews
Real life reviews from people like you
Slynd pill reviews
21 reviews
Used for 6 - 12 mo
34 years old
🇬🇧 UK
• 1 month ago
Generally happy with this pill, which I'm now able to get from my GP. It's much better than Desogestrel for me. I haven't had a period since I started it and no breakthrough bleeding either. My skin is great on this pill and my weight hasn't changed - if anything I lost a bit of weight, which unfortunately made my boobs smaller. I read this pill has a diuretic effect but I haven't noticed that at all. Initially I had headaches and some disturbed sleep, but these went away after the first month. My sex drive is lower but not to the point of it being an issue. I love that it has the safety of a 24-hour window, plus it's made my mood really stable and has stopped my periods.
Improved skin
1 more effect
0 helpful
0 comments
Used for 3 - 6 mo
31 years old
🇬🇧 UK
• 24th Feb 25
I have taken this pill for four months to help with endometriosis symptoms. Previously, I was on Eloine for about a year which worked greatly for me with minor side effects, but changed out of precautions due to having had two or three migraines with an aura. Within the first month of taking Slynd, my headaches became more frequent and intense (to such degree that I need to see a neurologist). Without changing my food habits, I gradually gained 8 kg in the four months of taking Slynd. I also have felt my mental health has been negatively affected by depressive feelings and mood swings. I am a mental health professional and was very surprised at this side effect, given my self-care routines and emotional regulation skills are usually optimal. I also developed adult acne, which I would have been ok with if it was the only side effect. The acne and weight gain have negatively affected my self-esteem. One good thing I experienced on Slynd is that my endometriosis cramps were less intense and that I was able to take this pill continuously, thereby skipping my periods and making endometriosis symptoms more manageable. As a result of this, I had more energy to work out.
Very negative mood
3 more effects
0 helpful
0 comments
Used for 3 - 6 mo
30 years old
🇬🇧 UK
• 2nd Jan 25
I’ve been on Slynd just over three months, and as someone who has tried several other mini pills this one seems to agree with me best. On other mini pills I experienced mild to moderate side effects, notably acne, spotting between periods/constantly and low mood. On Slynd I’ve only had very, very minor spotting and it’s infrequent. I haven’t yet had a period on Slynd but that’s not unusual for me on mini pills. Most notable is my skin, which has seen a noticeable and gradual improvement. Acne has been my biggest challenge on mini pills, with painful cystic acne requiring prescription topical creams for years on end. I’ve just started my fourth month on Slynd and seem to have turned a corner to where I have very little acne, if at all, and no cystic spots. My skin hasn’t been this clear in years! The only other side effects i’ve experienced, but cannot be 100% sure are related, are some moderate thirst in month 2/3 and a strange, weeks-long cramp in the bottom of my foot. I started eating more bananas to try and balance my potassium and the cramp has since gone. Rating 4 stars only because I’ve been on combination pills before (no longer can be on them) and I will always prefer the combination ones over mini pills. But I would say Slynd has been the closest to combination pills I’ve found yet.
Improved skin
0 helpful
0 comments
Used for 6 - 12 mo
34 years old
🇬🇧 UK
• 1 month ago
Generally happy with this pill, which I'm now able to get from my GP. It's much better than Desogestrel for me. I haven't had a period since I started it and no breakthrough bleeding either. My skin is great on this pill and my weight hasn't changed - if anything I lost a bit of weight, which unfortunately made my boobs smaller. I read this pill has a diuretic effect but I haven't noticed that at all. Initially I had headaches and some disturbed sleep, but these went away after the first month. My sex drive is lower but not to the point of it being an issue. I love that it has the safety of a 24-hour window, plus it's made my mood really stable and has stopped my periods.
Improved skin
1 more effect
0 helpful
0 comments
Used for 3 - 6 mo
31 years old
🇬🇧 UK
• 24th Feb 25
I have taken this pill for four months to help with endometriosis symptoms. Previously, I was on Eloine for about a year which worked greatly for me with minor side effects, but changed out of precautions due to having had two or three migraines with an aura. Within the first month of taking Slynd, my headaches became more frequent and intense (to such degree that I need to see a neurologist). Without changing my food habits, I gradually gained 8 kg in the four months of taking Slynd. I also have felt my mental health has been negatively affected by depressive feelings and mood swings. I am a mental health professional and was very surprised at this side effect, given my self-care routines and emotional regulation skills are usually optimal. I also developed adult acne, which I would have been ok with if it was the only side effect. The acne and weight gain have negatively affected my self-esteem. One good thing I experienced on Slynd is that my endometriosis cramps were less intense and that I was able to take this pill continuously, thereby skipping my periods and making endometriosis symptoms more manageable. As a result of this, I had more energy to work out.
Very negative mood
3 more effects
0 helpful
0 comments
Used for 3 - 6 mo
30 years old
🇬🇧 UK
• 2nd Jan 25
I’ve been on Slynd just over three months, and as someone who has tried several other mini pills this one seems to agree with me best. On other mini pills I experienced mild to moderate side effects, notably acne, spotting between periods/constantly and low mood. On Slynd I’ve only had very, very minor spotting and it’s infrequent. I haven’t yet had a period on Slynd but that’s not unusual for me on mini pills. Most notable is my skin, which has seen a noticeable and gradual improvement. Acne has been my biggest challenge on mini pills, with painful cystic acne requiring prescription topical creams for years on end. I’ve just started my fourth month on Slynd and seem to have turned a corner to where I have very little acne, if at all, and no cystic spots. My skin hasn’t been this clear in years! The only other side effects i’ve experienced, but cannot be 100% sure are related, are some moderate thirst in month 2/3 and a strange, weeks-long cramp in the bottom of my foot. I started eating more bananas to try and balance my potassium and the cramp has since gone. Rating 4 stars only because I’ve been on combination pills before (no longer can be on them) and I will always prefer the combination ones over mini pills. But I would say Slynd has been the closest to combination pills I’ve found yet.
Improved skin
0 helpful
0 comments
Desogestrel pill reviews
386 reviews
Used for 18 mo - 3 yr
18 years old
🇬🇧 UK
• today
i was put on this pill due to me being incredibly hormonal and 'hysterical' every month (on top of other issues i was facing). i was put on at 15-16 years of age i am now 18. my skin became more acne-like on cheeks and chin, whereas before it was just one or two. my breasts grew a lot, which was hard for me to come to terms with. thinking of coming off due to just 'having enough' and being worried about blood clots etc.
Somewhat positive mood
1 more effect
0 helpful
0 comments
Used for 1 - 3 mo
31 years old
🇬🇧 UK
• 1 day ago
I have been on this pill for a little over 10 weeks with the hopes of it stopping my period altogether but I spent more time bleeding than not. Sometimes little bits here and there, sometimes a lot and for 10+ days at a time. I found myself having a lot of down days and googling PPD symptoms. The worst thing I noticed was the brain fog. My ability to remember things and speak clear and cohesive sentences was just obliterated. I’m on day 2 post stopping and it feels a little better already although I have started my withdrawal bleed. I know you should give your body at least 3 months to settle after starting but honestly that was enough time for me. I just hope my cycle goes back to normal fairly soon!
Very negative mood
1 more effect
0 helpful
0 comments
Used for 5 - 8 yr
31 years old
🇬🇧 UK
• 6 days ago
Was on desogestrel for almost 8 years. Only got light spotting when I missed a pill, otherwise very easy adjusting to pill. I’ve stopped now as I’m trying to conceive and actually stopping has been an experience - I’ve been getting hormonal acne and my sex drive has shot through the roof! I also developed minor vaginismus (related to stress levels) on the pill and that seems to have gone away in the last month since I stopped desogestrel. I can update this in a few months time in case these symptoms are temporary or not.
Decreased sex drive
0 helpful
0 comments
Used for 18 mo - 3 yr
18 years old
🇬🇧 UK
• today
i was put on this pill due to me being incredibly hormonal and 'hysterical' every month (on top of other issues i was facing). i was put on at 15-16 years of age i am now 18. my skin became more acne-like on cheeks and chin, whereas before it was just one or two. my breasts grew a lot, which was hard for me to come to terms with. thinking of coming off due to just 'having enough' and being worried about blood clots etc.
Somewhat positive mood
1 more effect
0 helpful
0 comments
Used for 1 - 3 mo
31 years old
🇬🇧 UK
• 1 day ago
I have been on this pill for a little over 10 weeks with the hopes of it stopping my period altogether but I spent more time bleeding than not. Sometimes little bits here and there, sometimes a lot and for 10+ days at a time. I found myself having a lot of down days and googling PPD symptoms. The worst thing I noticed was the brain fog. My ability to remember things and speak clear and cohesive sentences was just obliterated. I’m on day 2 post stopping and it feels a little better already although I have started my withdrawal bleed. I know you should give your body at least 3 months to settle after starting but honestly that was enough time for me. I just hope my cycle goes back to normal fairly soon!
Very negative mood
1 more effect
0 helpful
0 comments
Used for 5 - 8 yr
31 years old
🇬🇧 UK
• 6 days ago
Was on desogestrel for almost 8 years. Only got light spotting when I missed a pill, otherwise very easy adjusting to pill. I’ve stopped now as I’m trying to conceive and actually stopping has been an experience - I’ve been getting hormonal acne and my sex drive has shot through the roof! I also developed minor vaginismus (related to stress levels) on the pill and that seems to have gone away in the last month since I stopped desogestrel. I can update this in a few months time in case these symptoms are temporary or not.
Decreased sex drive
0 helpful
0 comments
Used for 1 - 3 mo
20 years old
🇬🇧 UK
• 2 weeks ago
This is the WORST. My mental health plummeted on this pill, crying nearlt everyday. Not to mention i was bleeding medium heavy for 30+ days every single day. Really terrible effect i would not recommend. My doctor said to wait another week but after bleeding for a month straight i couldnt.
Top side effects not reported
1 helpful
0 comments
Used for 6 - 12 mo
19 years old
🇬🇧 UK
• 2 weeks ago
this was my first contraceptive pill i tried. in the first three months, i did struggle with lower mood and had consistent light bleeding that would last for over a week. later on, i adjusted better and eventually stopped having a period, with the occasional light bleeding from time to time. i experienced decreased sex drive and mentally has not been great but it has been manageable. i decided to stop this after 10 months due to suddenly getting worsened acne, which is not something i have struggled with since i was a young teenager
Somewhat negative mood
2 more effects
1 helpful
0 comments
Used for 1 - 3 mo
20 years old
🇬🇧 UK
• 3 weeks ago
Tried the mini pill because combined contraception scared me and I knew I had to go on something as I had recently got an abortion and suffered badly with period cramps. So far I’ve had very few side effects in the first month I had a couple of acne spots popping up due to the change in hormones but they stopped towards the end of my second month. I’ve been keeping an eye on my weight and it’s had no effect and I haven’t had an increase in appetite as I take the pill before I go to sleep at 9:30pm which I recommend so much. Overall my mood hasn’t been affected at all and I have stopped bleeding pretty much, I have had a small period recently on my 2nd month of pills but no cramps or bloating. Overall I’m super happy I started this pill of course it’s different for everybody my advice go with what you think is best for you and regularly check in with your doctor. It’s trial and error but don’t read into it online as everyone has different side effects this pill may work really well for you and not for others! I defo recommend though 🫶
Top side effects not reported
1 helpful
0 comments
Used for 3 - 6 mo
24 years old
🇬🇧 UK
• 5th Apr 25
3-6 months: (started the pill on 14/10/2024. I've done a review on my first 3 months so this is a follow up) Day 126 - 17/02/2024 – I’ve pretty much had 2 back to back periods with a 2 day break between which I really didn’t appreciate. They really hurt and I convinced myself something was wrong. I have made a doctors appointment to talk through everything. I’m just fed up with bleeding all of the time. I’m spending SO MUCH on pads it’s ridiculous. 12/03/2025 - I’m on my second week of my 6th month of the pill. I’ve kept having back to back periods and consulted the doctor. Because I’m coming up to 25 I had a routine smear (that came back clear) and the doctor did a pelvic exam and they recon it’s the pill that’s the cause of all the bleeding (which I assumed it was anyway. But better safe than sorry). I’m fed up of the bleeding but they’ve given me 6 more months after this to see if it settles. If not we’ll switch to something else. 5/4/2025 - I’m coming to the end of my 1st week in the 7th month of the pill. All I can say is that I’ve stopped bleeding/spotting for the most part. It’s been about 3 weeks since I last bled. So I guess the doctor was right. However, I had like a 1 day period at the beginning of the week it was painful and some period blood and then nothing since. But the last couple of days I’ve had some cramping as if a period wants to start but hasn’t yet. Overall, I think we’re getting back on track hopefully. Sorry I didn't reflect as much but it's pretty much been the same sort of story for the past 3 months
Worse skin
2 more effects
0 helpful
2 comments
Used for 5 - 8 yr
24 years old
🇬🇧 UK
• 22nd Mar 25
I’ve been taking the pill since I was 17, I’m now 25 and have never had an issue with it! I’ve not had any side effects at all! It stopped my periods after about 2/3 months and has been smooth sailing since then. I find the ‘window’ in which you can take it without it being considered a ‘missed pill’ is also really reassuring if you suffer with anxiety! Would definitely recommend.
Improved skin
0 helpful
0 comments
Used for 1 - 3 mo
40 years old
🇬🇧 UK
• 12th Mar 25
The chest pain was really awful, and that’s a big red flag. Even though a month might not seem like long enough to make a final judgment, the intensity of the chest pain and other symptoms definitely made me question whether this was the right pill for me. It's important to listen to your body, and in my case, the discomfort and pain outweighed any potential benefits. I would highly recommend discussing these symptoms with a healthcare provider to explore alternative options or further guidance
Somewhat positive mood
1 more effect
0 helpful
0 comments
Used for 6 - 12 mo
25 years old
🇬🇧 UK
• 3rd Mar 25
During the first 2-3 months of using Desogestrel, I'd have prolonged periods (14+ days) of spotting/bleeding around times when my period would normally have been. I wasn't having cramps or any other pain, it was just a little annoying to be bleeding like this. It did settle down after a few months and I stopped getting my period altogether. Overall, I found the contraception to be pretty easy to use (I don't really have issues remembering to take the pill), physical side-effects were pretty minimal and it was nice to not have a period after suffering with really heavy painful periods for years. I had a gnarly chronic UTI issue around this time, but don't think this was necessarily because of the pill, there's a million other reasons why that could have been happening. I eventually stopped using it because I noticed it was really having an effect on my mood. I'd have days every few weeks where something small in the morning would set me off and I wouldn't be able to stop crying all day, which was starting to affect my social life, relationships, and productivity. I decided to stop using it a few weeks before my partner and I shifted into being a long-distance relationship.
Gained weight
0 helpful
1 comments

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