Zelleta pill vs Desogestrel pill

Need help choosing? Speak to a doctor
Zelleta pill

£From £0.20/day

Desogestrel pill

£From £0.20/day

Overview

Rated 3.1

19 reviews

Daily

Frequency

93% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.7

391 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Zelleta pill ingredients

Main hormones in Zelleta pill

Less-Androgenic progestogen


Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen

What Lowdown reviewers say

32% somewhat negative

47% spotting

47% no impact

26% no impact

53% worse skin

Cycle return

67% don’t know impact

33% somewhat negative

43% stopped periods

53% lost sex drive

44% no impact

47% no impact on skin

Cycle return

41% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

Try it now

£From £0.20/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Zelleta pill reviews

19 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
26 years old
🇬🇧 UK
  •  3 weeks ago

Zelleta pill  

I started using this pill to help with endometriosis symptoms. Instead of making me bleed less, I was bleeding every 12 days, and for about a week at a time which was exhausting and painful. I would also get night sweats and felt very low in mood at times. I tried it for 5 months but I couldn’t deal with 2 periods a month, so I have switched to a combined pill to see if that is any better.

Read more

Somewhat negative mood

1 more effect

0 helpful

1 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1st Apr 25

Zelleta pill  

Since taking the zelleta pull my mood has gotten a lot worse. I catch myself crying over little things I would have never cried about before. I used to take the cerelle pill which worked well for me but now I get irritated easily and lasch out at my boyfriend a lot.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Having never tried the mini-pill before, for the couple of months I finally thought I'd found the right contraception for me. Unfortunately, after about three months of taking it my periods became irregular, and I ended up having a really long period followed by two months of having no period. The issue was every time I had a period, the period itself would last longer and longer each time. After one period that lasted over two weeks and made me feel exhausted and anxious, I decided to stop taking it. They weren't light periods either, they were heavy with clots. Such a shame as I felt pretty good for the first couple of months, much better than I had done on any combined pill I had taken.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
26 years old
🇬🇧 UK
  •  3 weeks ago

Zelleta pill  

I started using this pill to help with endometriosis symptoms. Instead of making me bleed less, I was bleeding every 12 days, and for about a week at a time which was exhausting and painful. I would also get night sweats and felt very low in mood at times. I tried it for 5 months but I couldn’t deal with 2 periods a month, so I have switched to a combined pill to see if that is any better.


Somewhat negative mood

1 more effect

0 helpful

1 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1st Apr 25

Zelleta pill  

Since taking the zelleta pull my mood has gotten a lot worse. I catch myself crying over little things I would have never cried about before. I used to take the cerelle pill which worked well for me but now I get irritated easily and lasch out at my boyfriend a lot.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Having never tried the mini-pill before, for the couple of months I finally thought I'd found the right contraception for me. Unfortunately, after about three months of taking it my periods became irregular, and I ended up having a really long period followed by two months of having no period. The issue was every time I had a period, the period itself would last longer and longer each time. After one period that lasted over two weeks and made me feel exhausted and anxious, I decided to stop taking it. They weren't light periods either, they were heavy with clots. Such a shame as I felt pretty good for the first couple of months, much better than I had done on any combined pill I had taken.


Somewhat negative mood

1 more effect

0 helpful

0 comments


Desogestrel pill reviews

391 reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
43 years old
🇬🇧 UK
  •  4 days ago

Desogestrel pill  

I’m very satisfied with the pill. I only been taking it for few weeks but my mental health improved so much ! I can’t actually believe it. I used to suffer mood swings due to hormonal fluctuations . None of this is happening . Very happy. No side effects either


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
26 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I was so concerned about weight gain and mood changes but have not experienced this. I have barely any side effects and have had a really positive experience!


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I use this pill in combination with a copper coil and it has helped enormously with my PMDD symptoms. I used to really struggle around ovulation with feeling very unwell and now that I don’t have a cycle everything is a lot calmer. I’ve had some spotting and I’m sweating more but it’s much better than having hellish and painful periods. I now don’t have periods at all, which is so much less stressful. I feel like I can finally enjoy my life.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
43 years old
🇬🇧 UK
  •  4 days ago

Desogestrel pill  

I’m very satisfied with the pill. I only been taking it for few weeks but my mental health improved so much ! I can’t actually believe it. I used to suffer mood swings due to hormonal fluctuations . None of this is happening . Very happy. No side effects either


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
26 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I was so concerned about weight gain and mood changes but have not experienced this. I have barely any side effects and have had a really positive experience!


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I use this pill in combination with a copper coil and it has helped enormously with my PMDD symptoms. I used to really struggle around ovulation with feeling very unwell and now that I don’t have a cycle everything is a lot calmer. I’ve had some spotting and I’m sweating more but it’s much better than having hellish and painful periods. I now don’t have periods at all, which is so much less stressful. I feel like I can finally enjoy my life.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
25 years old
🇬🇧 UK
  •  3 weeks ago

Desogestrel pill  

I must say that this pill absolutely saved my life. Suffering from severe endometriosis pain & PMDD and it reversed the effects of that. I have control of my moods and body back and I’m so grateful. I must leave a positive review because it’s not all bad. The beginning was rocky with irregular bleeding but this stopped after 8 months or so. It was worth it.


Very positive mood

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

I was put on this pill after I suffered from bad migraines from the combined pill- I wanted to try contraception to tackle my low moods, PCOS and acne. I became so depressed over the course of about 3 months, to the point where I went to the GP to try and get some therapy/talk about possibly taking antidepressants. Straight away the GP was like 'oh just stop taking the pill'- I did and a few months later I felt normal again. Literally can't believe that GPs prescribe this stuff without giving you proper warning- I felt like an empty shell of a person for a few months literally all because of this pill.


Very negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
18 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

i was put on this pill due to me being incredibly hormonal and 'hysterical' every month (on top of other issues i was facing). i was put on at 15-16 years of age i am now 18. my skin became more acne-like on cheeks and chin, whereas before it was just one or two. my breasts grew a lot, which was hard for me to come to terms with. thinking of coming off due to just 'having enough' and being worried about blood clots etc.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
31 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

I have been on this pill for a little over 10 weeks with the hopes of it stopping my period altogether but I spent more time bleeding than not. Sometimes little bits here and there, sometimes a lot and for 10+ days at a time. I found myself having a lot of down days and googling PPD symptoms. The worst thing I noticed was the brain fog. My ability to remember things and speak clear and cohesive sentences was just obliterated. I’m on day 2 post stopping and it feels a little better already although I have started my withdrawal bleed. I know you should give your body at least 3 months to settle after starting but honestly that was enough time for me. I just hope my cycle goes back to normal fairly soon!


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 5 - 8 yr
31 years old
🇬🇧 UK
  •  9th May 25

Desogestrel pill  

Was on desogestrel for almost 8 years. Only got light spotting when I missed a pill, otherwise very easy adjusting to pill. I’ve stopped now as I’m trying to conceive and actually stopping has been an experience - I’ve been getting hormonal acne and my sex drive has shot through the roof! I also developed minor vaginismus (related to stress levels) on the pill and that seems to have gone away in the last month since I stopped desogestrel. I can update this in a few months time in case these symptoms are temporary or not.


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
20 years old
🇬🇧 UK
  •  2nd May 25

Desogestrel pill  

This is the WORST. My mental health plummeted on this pill, crying nearlt everyday. Not to mention i was bleeding medium heavy for 30+ days every single day. Really terrible effect i would not recommend. My doctor said to wait another week but after bleeding for a month straight i couldnt.


Top side effects not reported

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
19 years old
🇬🇧 UK
  •  2nd May 25

Desogestrel pill  

this was my first contraceptive pill i tried. in the first three months, i did struggle with lower mood and had consistent light bleeding that would last for over a week. later on, i adjusted better and eventually stopped having a period, with the occasional light bleeding from time to time. i experienced decreased sex drive and mentally has not been great but it has been manageable. i decided to stop this after 10 months due to suddenly getting worsened acne, which is not something i have struggled with since i was a young teenager


Somewhat negative mood

2 more effects

1 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Zelleta pill with other contraceptives

Compare the Desogestrel pill with other contraceptives

Order online

Order online now

Use our online prescription in under 5 mins

  • No GP appointment needed

  • Free standard delivery

Speak to a doctor

Not sure yet? Speak to a doctor

Schedule an appointment now

87% of women are happier with their contraceptive choice after speaking with one of The Lowdown's doctors

The Lowdown Footer

Women's health, reviewed.

Get the best women’s health info in your inbox

You are signing up to receive The Lowdown's latest findings and news in women's health. Your data will be used in accordance with our Privacy & Cookie policy

Built by doctors and experts

Our tools are made by medical professionals for your peace of mind

Our website uses affiliate links and we may earn a small commission if you click on them