Desogestrel pill vs Zelleta pill

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Desogestrel pill

£From £0.20/day

Zelleta pill

£From £0.20/day

Overview

Rated 2.6

381 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 3.2

18 reviews

Daily

Frequency

93% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen


Zelleta pill ingredients

Main hormones in Zelleta pill

Less-Androgenic progestogen

What Lowdown reviewers say

34% somewhat negative

43% stopped periods

54% lost sex drive

43% no impact

46% no impact on skin

Cycle return

40% don’t know impact

28% somewhat negative

44% spotting

44% no impact

28% gained weight

50% worse skin

Cycle return

67% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

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£From £0.20/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Desogestrel pill reviews

381 reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
20 years old
🇬🇧 UK
  •  2 days ago

Desogestrel pill  

Tried the mini pill because combined contraception scared me and I knew I had to go on something as I had recently got an abortion and suffered badly with period cramps. So far I’ve had very few side effects in the first month I had a couple of acne spots popping up due to the change in hormones but they stopped towards the end of my second month. I’ve been keeping an eye on my weight and it’s had no effect and I haven’t had an increase in appetite as I take the pill before I go to sleep at 9:30pm which I recommend so much. Overall my mood hasn’t been affected at all and I have stopped bleeding pretty much, I have had a small period recently on my 2nd month of pills but no cramps or bloating. Overall I’m super happy I started this pill of course it’s different for everybody my advice go with what you think is best for you and regularly check in with your doctor. It’s trial and error but don’t read into it online as everyone has different side effects this pill may work really well for you and not for others! I defo recommend though 🫶

Read more

Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
24 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

3-6 months: (started the pill on 14/10/2024. I've done a review on my first 3 months so this is a follow up) Day 126 - 17/02/2024 – I’ve pretty much had 2 back to back periods with a 2 day break between which I really didn’t appreciate. They really hurt and I convinced myself something was wrong. I have made a doctors appointment to talk through everything. I’m just fed up with bleeding all of the time. I’m spending SO MUCH on pads it’s ridiculous. 12/03/2025 - I’m on my second week of my 6th month of the pill. I’ve kept having back to back periods and consulted the doctor. Because I’m coming up to 25 I had a routine smear (that came back clear) and the doctor did a pelvic exam and they recon it’s the pill that’s the cause of all the bleeding (which I assumed it was anyway. But better safe than sorry). I’m fed up of the bleeding but they’ve given me 6 more months after this to see if it settles. If not we’ll switch to something else. 5/4/2025 - I’m coming to the end of my 1st week in the 7th month of the pill. All I can say is that I’ve stopped bleeding/spotting for the most part. It’s been about 3 weeks since I last bled. So I guess the doctor was right. However, I had like a 1 day period at the beginning of the week it was painful and some period blood and then nothing since. But the last couple of days I’ve had some cramping as if a period wants to start but hasn’t yet. Overall, I think we’re getting back on track hopefully. Sorry I didn't reflect as much but it's pretty much been the same sort of story for the past 3 months


Worse skin

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 5 - 8 yr
24 years old
🇬🇧 UK
  •  22nd Mar 25

Desogestrel pill  

I’ve been taking the pill since I was 17, I’m now 25 and have never had an issue with it! I’ve not had any side effects at all! It stopped my periods after about 2/3 months and has been smooth sailing since then. I find the ‘window’ in which you can take it without it being considered a ‘missed pill’ is also really reassuring if you suffer with anxiety! Would definitely recommend.


Improved skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
20 years old
🇬🇧 UK
  •  2 days ago

Desogestrel pill  

Tried the mini pill because combined contraception scared me and I knew I had to go on something as I had recently got an abortion and suffered badly with period cramps. So far I’ve had very few side effects in the first month I had a couple of acne spots popping up due to the change in hormones but they stopped towards the end of my second month. I’ve been keeping an eye on my weight and it’s had no effect and I haven’t had an increase in appetite as I take the pill before I go to sleep at 9:30pm which I recommend so much. Overall my mood hasn’t been affected at all and I have stopped bleeding pretty much, I have had a small period recently on my 2nd month of pills but no cramps or bloating. Overall I’m super happy I started this pill of course it’s different for everybody my advice go with what you think is best for you and regularly check in with your doctor. It’s trial and error but don’t read into it online as everyone has different side effects this pill may work really well for you and not for others! I defo recommend though 🫶


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
24 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

3-6 months: (started the pill on 14/10/2024. I've done a review on my first 3 months so this is a follow up) Day 126 - 17/02/2024 – I’ve pretty much had 2 back to back periods with a 2 day break between which I really didn’t appreciate. They really hurt and I convinced myself something was wrong. I have made a doctors appointment to talk through everything. I’m just fed up with bleeding all of the time. I’m spending SO MUCH on pads it’s ridiculous. 12/03/2025 - I’m on my second week of my 6th month of the pill. I’ve kept having back to back periods and consulted the doctor. Because I’m coming up to 25 I had a routine smear (that came back clear) and the doctor did a pelvic exam and they recon it’s the pill that’s the cause of all the bleeding (which I assumed it was anyway. But better safe than sorry). I’m fed up of the bleeding but they’ve given me 6 more months after this to see if it settles. If not we’ll switch to something else. 5/4/2025 - I’m coming to the end of my 1st week in the 7th month of the pill. All I can say is that I’ve stopped bleeding/spotting for the most part. It’s been about 3 weeks since I last bled. So I guess the doctor was right. However, I had like a 1 day period at the beginning of the week it was painful and some period blood and then nothing since. But the last couple of days I’ve had some cramping as if a period wants to start but hasn’t yet. Overall, I think we’re getting back on track hopefully. Sorry I didn't reflect as much but it's pretty much been the same sort of story for the past 3 months


Worse skin

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 5 - 8 yr
24 years old
🇬🇧 UK
  •  22nd Mar 25

Desogestrel pill  

I’ve been taking the pill since I was 17, I’m now 25 and have never had an issue with it! I’ve not had any side effects at all! It stopped my periods after about 2/3 months and has been smooth sailing since then. I find the ‘window’ in which you can take it without it being considered a ‘missed pill’ is also really reassuring if you suffer with anxiety! Would definitely recommend.


Improved skin

0 helpful

0 comments


Zelleta pill reviews

18 reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1 month ago

Zelleta pill  

Since taking the zelleta pull my mood has gotten a lot worse. I catch myself crying over little things I would have never cried about before. I used to take the cerelle pill which worked well for me but now I get irritated easily and lasch out at my boyfriend a lot.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Having never tried the mini-pill before, for the couple of months I finally thought I'd found the right contraception for me. Unfortunately, after about three months of taking it my periods became irregular, and I ended up having a really long period followed by two months of having no period. The issue was every time I had a period, the period itself would last longer and longer each time. After one period that lasted over two weeks and made me feel exhausted and anxious, I decided to stop taking it. They weren't light periods either, they were heavy with clots. Such a shame as I felt pretty good for the first couple of months, much better than I had done on any combined pill I had taken.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
30 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Switched to Zelleta (Desogestrel) from the combined pill because of side effects. Had one unusually long period (9 days) one month after starting Zelleta, after that my periods stopped completely and I only had minor spotting every now and then which almost completely disappeared over time. I gradually noticed a complete loss of sex drive which bothered me a lot and I ended up switching to non-hormonal contraception instead because of this.


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1 month ago

Zelleta pill  

Since taking the zelleta pull my mood has gotten a lot worse. I catch myself crying over little things I would have never cried about before. I used to take the cerelle pill which worked well for me but now I get irritated easily and lasch out at my boyfriend a lot.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Having never tried the mini-pill before, for the couple of months I finally thought I'd found the right contraception for me. Unfortunately, after about three months of taking it my periods became irregular, and I ended up having a really long period followed by two months of having no period. The issue was every time I had a period, the period itself would last longer and longer each time. After one period that lasted over two weeks and made me feel exhausted and anxious, I decided to stop taking it. They weren't light periods either, they were heavy with clots. Such a shame as I felt pretty good for the first couple of months, much better than I had done on any combined pill I had taken.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
30 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Switched to Zelleta (Desogestrel) from the combined pill because of side effects. Had one unusually long period (9 days) one month after starting Zelleta, after that my periods stopped completely and I only had minor spotting every now and then which almost completely disappeared over time. I gradually noticed a complete loss of sex drive which bothered me a lot and I ended up switching to non-hormonal contraception instead because of this.


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
24 years old
🇬🇧 UK
  •  6th Feb 25

Zelleta pill  

I was on Rigevidon for about 8 years and got on really well with it. After starting with migraines with aura, I had to change to a mini pill. I can’t believe the difference in my mental health, weight, spots. Everything has just taken a down hill. I’ve been bleeding nearly constantly for the last month, so I’m going to have to find something new. On top of that, my sex drive is low, mood is low, always tired, spots all over my back and shoulders and weight gain.


Somewhat negative mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
30 years old
🇬🇧 UK
  •  1st Feb 25

Zelleta pill  

Would not stop bleeding for 3 months and in turn felt so low.


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
23 years old
🇬🇧 UK
  •  2nd Jan 25

Zelleta pill  

I started this pill after being on the implant for years. I was initially scared, but this is not very different from the implant. The first six or so months are MUCH easier than when I was on the implant. I feel much more emotionally stable, with an increased libido compared to my old BC method. I like the flexibility of being able to stop taking it when I want. I take it at night which helps regulate my emotions and I feel more chilled out on this pill (I have severe anxiety). I've had no periods at all on this pill. The only downside is remembering to take it but for me the flexibility is worth it. I've also noticed more sweating and I get quite hot.


Somewhat positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  29th Nov 24

Zelleta pill  

I have only been taking this pill for just over a month, but so far I am really happy with it. No change in moods, sex drive or skin. My boobs have grown lot - which I'm not mad about! Although I do feel slightly frumpy, as though I have put on a bit of weight - but it isn't hugely noticeable I don't think. I did have spotting for the first 2.5 weeks of using the pill which has now stopped completely.


Gained weight

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  13th May 24

Zelleta pill  

Overall, I was happy with this pill. I am not currently on it as I'm in between prescriptions and its been difficult contacting my doctor. However, the last week without it has made me realise how I was benefitting from it. I used to get mood swings quite often which disappeared when on this pill. The first month, my mood swings were still there like before and I found that I was more likely to cry over small things but this went away after the first 4 weeks. Before, I would also get medium pain cramps that lasted nearly the whole day for about 2 weeks on and off every month. This went down to small cramps for an hour maybe one or twice a month which was definitely a positive. I did get one or two more spots on my face which was annoying as I've struggled with my skin for a while and was finally starting to clear it up before starting the pill but this wasn't a significant impact because I was used to my stubborn skin. I also got spots on my back and chest, but these started going away again after about 6-8 weeks. The main impact I had was my period. It went from being pretty regular and heavy for 6-7 days every month to a very light period (ranging from light/medium to basically only spotting) that lasted for 3 weeks. Although without cramps and because it was so light it didn't impact me much (it was more an inconvenience). After this, I wouldn't get my period for over a month (about 5 weeks) and then it started again. I understand that this is what would put most people off getting the pill and it was what I had been dreading the most but I realised that it wasn't as bad as I thought as most days I could get away with just a panty liner rather than an actual pad or tampon (and it reassured me I wasn't pregnant).


Somewhat positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  9th Apr 24

Zelleta pill  

I couldn’t be happier with this pill. After having a break from contraception and using FAM and falling pregnant twice, I decided I needed to go back on birth control. I initially tried the copper coil but it expelled after 24 hours and I didn’t want to go through the insertion process again. I went to the doctor and she’s said to give the mini pill a go, and I was prescribed Zelleta. I was really nervous as I have previously been in the combined pill for 7 years and it really impacted my mood so I was hesitant to try a pill again, but the doctor told me my body could react differently to the mini pill and she was right. The first two weeks I had headaches almost everyday, and was feeling extremely tired but I think this was down to my body getting used to the pill. After the three week mark they both disappeared. I had no loss of sex drive, I would actually say it’s increased which took me by surprise. I’ve lost around 8lbs and I feel like I have more energy. The only downside for me is my skin (previously completely clear) has had some breakouts but I will take it. My low mood and anxiety has decreased significantly. I was so hesitant to go back on the pill but when your doctor says they’re not all the same and you just have to find the right one for you, listen to them because it’s so true.


Very positive mood

2 more effects

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  28th Mar 24

Zelleta pill  

The main side effect I experienced at the beginning of taking this pill was nausea, mainly after I had taken the pill but also throughout the day to the point where I thought I could be pregnant but it has subsided. I have started getting very irregular periods and regular spotting but I don’t really mind it too much, generally they’re a lot lighter and not painful. I have gotten a few more breakouts but they’re quite small, and could be due to other factors - do not let this put you off this pill. In terms of mood I have been crying more but not necessarily because I’m sadder at all? just out of happiness etc haha. No impact at all on sex drive etc yes. Overall a pretty good experience so far (but don’t want to jinx it)


Worse skin

0 helpful

0 comments

Contraceptive alternatives and comparisons

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Compare the Zelleta pill with other contraceptives

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