Desogestrel pill vs Zelleta pill

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Desogestrel pill

£From £0.20/day

Zelleta pill

£From £0.20/day

Overview

Rated 2.7

388 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 3.1

19 reviews

Daily

Frequency

93% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen


Zelleta pill ingredients

Main hormones in Zelleta pill

Less-Androgenic progestogen

What Lowdown reviewers say

33% somewhat negative

43% stopped periods

53% lost sex drive

43% no impact

47% no impact on skin

Cycle return

41% don’t know impact

32% somewhat negative

47% spotting

47% no impact

26% no impact

53% worse skin

Cycle return

67% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

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£From £0.20/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Desogestrel pill reviews

388 reviews

Progestogen-only / Mini pill  
Used for 12 - 18 mo
25 years old
🇬🇧 UK
  •  2 days ago

Desogestrel pill  

I must say that this pill absolutely saved my life. Suffering from severe endometriosis pain & PMDD and it reversed the effects of that. I have control of my moods and body back and I’m so grateful. I must leave a positive review because it’s not all bad. The beginning was rocky with irregular bleeding but this stopped after 8 months or so. It was worth it.

Read more

Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  1 week ago

Desogestrel pill  

I was put on this pill after I suffered from bad migraines from the combined pill- I wanted to try contraception to tackle my low moods, PCOS and acne. I became so depressed over the course of about 3 months, to the point where I went to the GP to try and get some therapy/talk about possibly taking antidepressants. Straight away the GP was like 'oh just stop taking the pill'- I did and a few months later I felt normal again. Literally can't believe that GPs prescribe this stuff without giving you proper warning- I felt like an empty shell of a person for a few months literally all because of this pill.


Very negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
18 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

i was put on this pill due to me being incredibly hormonal and 'hysterical' every month (on top of other issues i was facing). i was put on at 15-16 years of age i am now 18. my skin became more acne-like on cheeks and chin, whereas before it was just one or two. my breasts grew a lot, which was hard for me to come to terms with. thinking of coming off due to just 'having enough' and being worried about blood clots etc.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
25 years old
🇬🇧 UK
  •  2 days ago

Desogestrel pill  

I must say that this pill absolutely saved my life. Suffering from severe endometriosis pain & PMDD and it reversed the effects of that. I have control of my moods and body back and I’m so grateful. I must leave a positive review because it’s not all bad. The beginning was rocky with irregular bleeding but this stopped after 8 months or so. It was worth it.


Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  1 week ago

Desogestrel pill  

I was put on this pill after I suffered from bad migraines from the combined pill- I wanted to try contraception to tackle my low moods, PCOS and acne. I became so depressed over the course of about 3 months, to the point where I went to the GP to try and get some therapy/talk about possibly taking antidepressants. Straight away the GP was like 'oh just stop taking the pill'- I did and a few months later I felt normal again. Literally can't believe that GPs prescribe this stuff without giving you proper warning- I felt like an empty shell of a person for a few months literally all because of this pill.


Very negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
18 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

i was put on this pill due to me being incredibly hormonal and 'hysterical' every month (on top of other issues i was facing). i was put on at 15-16 years of age i am now 18. my skin became more acne-like on cheeks and chin, whereas before it was just one or two. my breasts grew a lot, which was hard for me to come to terms with. thinking of coming off due to just 'having enough' and being worried about blood clots etc.


Somewhat positive mood

1 more effect

0 helpful

0 comments


Zelleta pill reviews

19 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
26 years old
🇬🇧 UK
  •  5 days ago

Zelleta pill  

I started using this pill to help with endometriosis symptoms. Instead of making me bleed less, I was bleeding every 12 days, and for about a week at a time which was exhausting and painful. I would also get night sweats and felt very low in mood at times. I tried it for 5 months but I couldn’t deal with 2 periods a month, so I have switched to a combined pill to see if that is any better.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1st Apr 25

Zelleta pill  

Since taking the zelleta pull my mood has gotten a lot worse. I catch myself crying over little things I would have never cried about before. I used to take the cerelle pill which worked well for me but now I get irritated easily and lasch out at my boyfriend a lot.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Having never tried the mini-pill before, for the couple of months I finally thought I'd found the right contraception for me. Unfortunately, after about three months of taking it my periods became irregular, and I ended up having a really long period followed by two months of having no period. The issue was every time I had a period, the period itself would last longer and longer each time. After one period that lasted over two weeks and made me feel exhausted and anxious, I decided to stop taking it. They weren't light periods either, they were heavy with clots. Such a shame as I felt pretty good for the first couple of months, much better than I had done on any combined pill I had taken.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
26 years old
🇬🇧 UK
  •  5 days ago

Zelleta pill  

I started using this pill to help with endometriosis symptoms. Instead of making me bleed less, I was bleeding every 12 days, and for about a week at a time which was exhausting and painful. I would also get night sweats and felt very low in mood at times. I tried it for 5 months but I couldn’t deal with 2 periods a month, so I have switched to a combined pill to see if that is any better.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1st Apr 25

Zelleta pill  

Since taking the zelleta pull my mood has gotten a lot worse. I catch myself crying over little things I would have never cried about before. I used to take the cerelle pill which worked well for me but now I get irritated easily and lasch out at my boyfriend a lot.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Having never tried the mini-pill before, for the couple of months I finally thought I'd found the right contraception for me. Unfortunately, after about three months of taking it my periods became irregular, and I ended up having a really long period followed by two months of having no period. The issue was every time I had a period, the period itself would last longer and longer each time. After one period that lasted over two weeks and made me feel exhausted and anxious, I decided to stop taking it. They weren't light periods either, they were heavy with clots. Such a shame as I felt pretty good for the first couple of months, much better than I had done on any combined pill I had taken.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
30 years old
🇬🇧 UK
  •  8th Feb 25

Zelleta pill  

Switched to Zelleta (Desogestrel) from the combined pill because of side effects. Had one unusually long period (9 days) one month after starting Zelleta, after that my periods stopped completely and I only had minor spotting every now and then which almost completely disappeared over time. I gradually noticed a complete loss of sex drive which bothered me a lot and I ended up switching to non-hormonal contraception instead because of this.


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
24 years old
🇬🇧 UK
  •  6th Feb 25

Zelleta pill  

I was on Rigevidon for about 8 years and got on really well with it. After starting with migraines with aura, I had to change to a mini pill. I can’t believe the difference in my mental health, weight, spots. Everything has just taken a down hill. I’ve been bleeding nearly constantly for the last month, so I’m going to have to find something new. On top of that, my sex drive is low, mood is low, always tired, spots all over my back and shoulders and weight gain.


Somewhat negative mood

3 more effects

0 helpful

1 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
30 years old
🇬🇧 UK
  •  1st Feb 25

Zelleta pill  

Would not stop bleeding for 3 months and in turn felt so low.


Somewhat negative mood

2 more effects

0 helpful

1 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
23 years old
🇬🇧 UK
  •  2nd Jan 25

Zelleta pill  

I started this pill after being on the implant for years. I was initially scared, but this is not very different from the implant. The first six or so months are MUCH easier than when I was on the implant. I feel much more emotionally stable, with an increased libido compared to my old BC method. I like the flexibility of being able to stop taking it when I want. I take it at night which helps regulate my emotions and I feel more chilled out on this pill (I have severe anxiety). I've had no periods at all on this pill. The only downside is remembering to take it but for me the flexibility is worth it. I've also noticed more sweating and I get quite hot.


Somewhat positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  29th Nov 24

Zelleta pill  

I have only been taking this pill for just over a month, but so far I am really happy with it. No change in moods, sex drive or skin. My boobs have grown lot - which I'm not mad about! Although I do feel slightly frumpy, as though I have put on a bit of weight - but it isn't hugely noticeable I don't think. I did have spotting for the first 2.5 weeks of using the pill which has now stopped completely.


Gained weight

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  13th May 24

Zelleta pill  

Overall, I was happy with this pill. I am not currently on it as I'm in between prescriptions and its been difficult contacting my doctor. However, the last week without it has made me realise how I was benefitting from it. I used to get mood swings quite often which disappeared when on this pill. The first month, my mood swings were still there like before and I found that I was more likely to cry over small things but this went away after the first 4 weeks. Before, I would also get medium pain cramps that lasted nearly the whole day for about 2 weeks on and off every month. This went down to small cramps for an hour maybe one or twice a month which was definitely a positive. I did get one or two more spots on my face which was annoying as I've struggled with my skin for a while and was finally starting to clear it up before starting the pill but this wasn't a significant impact because I was used to my stubborn skin. I also got spots on my back and chest, but these started going away again after about 6-8 weeks. The main impact I had was my period. It went from being pretty regular and heavy for 6-7 days every month to a very light period (ranging from light/medium to basically only spotting) that lasted for 3 weeks. Although without cramps and because it was so light it didn't impact me much (it was more an inconvenience). After this, I wouldn't get my period for over a month (about 5 weeks) and then it started again. I understand that this is what would put most people off getting the pill and it was what I had been dreading the most but I realised that it wasn't as bad as I thought as most days I could get away with just a panty liner rather than an actual pad or tampon (and it reassured me I wasn't pregnant).


Somewhat positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  9th Apr 24

Zelleta pill  

I couldn’t be happier with this pill. After having a break from contraception and using FAM and falling pregnant twice, I decided I needed to go back on birth control. I initially tried the copper coil but it expelled after 24 hours and I didn’t want to go through the insertion process again. I went to the doctor and she’s said to give the mini pill a go, and I was prescribed Zelleta. I was really nervous as I have previously been in the combined pill for 7 years and it really impacted my mood so I was hesitant to try a pill again, but the doctor told me my body could react differently to the mini pill and she was right. The first two weeks I had headaches almost everyday, and was feeling extremely tired but I think this was down to my body getting used to the pill. After the three week mark they both disappeared. I had no loss of sex drive, I would actually say it’s increased which took me by surprise. I’ve lost around 8lbs and I feel like I have more energy. The only downside for me is my skin (previously completely clear) has had some breakouts but I will take it. My low mood and anxiety has decreased significantly. I was so hesitant to go back on the pill but when your doctor says they’re not all the same and you just have to find the right one for you, listen to them because it’s so true.


Very positive mood

2 more effects

1 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Desogestrel pill with other contraceptives

Compare the Zelleta pill with other contraceptives

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