Injection vs Progestogen-only / Mini pill

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Injection

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Progestogen-only / Mini pill

£From £0.22/day

Overview

Rated 2.9

315 reviews

Every 2-3 months

Frequency

94% - 99+%

Effectiveness

None

Blood clot risk

Short term

Effect on fertility

Rated 2.7

1516 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Injection ingredients

Main hormones in Injection

progestogen


Progestogen-only / Mini pill ingredients

Main hormones in Progestogen-only / Mini pill

progestogen

What Lowdown reviewers say

31% somewhat negative

70% stopped periods

57% lost sex drive

47% gained weight

46% no impact on skin

Cycle return

43% don’t know impact

32% somewhat negative

44% stopped periods

49% lost sex drive

44% no impact

46% no impact on skin

Cycle return

40% don’t know impact

Benefits: What this contraceptive can help with

Endometriosis

Heavy periods

Period pain

Period pain

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£From £0.22/day

Check out our latest reviews

Real life reviews from people like you

Injection reviews

315 reviews

Injection  
Used for 18 mo - 3 yr
24 years old
🇬🇧 UK
  •  1 month ago

Depo-Provera injection  

I was on it 2+ years, decided to stop as ‘apparently’ you’re not supposed to be on it longer than 2 years. Was not told that, only found out from women in the news with adverse side effects. Positives, periods completely stopped, all side effects along with it disappeared. Negatives, I feel over these years, I have lost all sex drive with my partner and sexual desire in general (self touch also). On reflection, I feel I lost all emotions other than anger, frustration, which became quite difficult in my relationship, almost to the point of breaking (6+ years). To note, you may experience what I can only describe, drug withdrawal symptoms when you come off the injection. I had severe migraines for 72+ hours, hot cold sweats, swollen breasts for a while, really bad fatigue and severe nausea to the point of being sick again and again and again. The rush of hormones was and still is horrific, total mess. Still waiting for a period… however you can be waiting for up to 18 months to bleed, whilst still ovulating and everything else, so be warned. I don’t believe there is any contraception that is truly the best, but I wouldn’t recommend this to anyone. The combined pill was better but you just have to be on top of taking it at the same time everyday, which was an issue for me being a shift worker (not always reliable).

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Somewhat negative mood

1 more effect

0 helpful

0 comments

Injection  
Used for 12 - 18 mo
21 years old
🇬🇧 UK
  •  5th Jul 26

Noristerat injection  

Right now l feel enlargement of breast and my periods are spotting


Somewhat negative mood

1 more effect

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
20 years old
🇬🇧 UK
  •  17th Jun 26

Depo-Provera injection  

I’ve been getting this shot ever since my first period and before I started taking it, I was having heavy period cramps and I disliked the constant pain from my period cramps


Very positive mood

1 more effect

0 helpful

0 comments

Injection  
Used for 18 mo - 3 yr
24 years old
🇬🇧 UK
  •  1 month ago

Depo-Provera injection  

I was on it 2+ years, decided to stop as ‘apparently’ you’re not supposed to be on it longer than 2 years. Was not told that, only found out from women in the news with adverse side effects. Positives, periods completely stopped, all side effects along with it disappeared. Negatives, I feel over these years, I have lost all sex drive with my partner and sexual desire in general (self touch also). On reflection, I feel I lost all emotions other than anger, frustration, which became quite difficult in my relationship, almost to the point of breaking (6+ years). To note, you may experience what I can only describe, drug withdrawal symptoms when you come off the injection. I had severe migraines for 72+ hours, hot cold sweats, swollen breasts for a while, really bad fatigue and severe nausea to the point of being sick again and again and again. The rush of hormones was and still is horrific, total mess. Still waiting for a period… however you can be waiting for up to 18 months to bleed, whilst still ovulating and everything else, so be warned. I don’t believe there is any contraception that is truly the best, but I wouldn’t recommend this to anyone. The combined pill was better but you just have to be on top of taking it at the same time everyday, which was an issue for me being a shift worker (not always reliable).


Somewhat negative mood

1 more effect

0 helpful

0 comments

Injection  
Used for 12 - 18 mo
21 years old
🇬🇧 UK
  •  5th Jul 26

Noristerat injection  

Right now l feel enlargement of breast and my periods are spotting


Somewhat negative mood

1 more effect

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
20 years old
🇬🇧 UK
  •  17th Jun 26

Depo-Provera injection  

I’ve been getting this shot ever since my first period and before I started taking it, I was having heavy period cramps and I disliked the constant pain from my period cramps


Very positive mood

1 more effect

0 helpful

0 comments


Progestogen-only / Mini pill reviews

1516 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
27 years old
🇬🇧 UK
  •  1 day ago

Slynd pill  

I was put on this after being diagnosed with PMDD. I was wary to go on a hormonal pill after having a horrible time when I was a teenager on the combined pill but this has been lifechanging. I was losing 2 weeks out of the month due to my mood, especially with my AUDHD too. I have now got them back. I feel so much more level and calm. For the first 3 months, I had vaginal dryness (which made sex painful), spotting and nausea but this has now completely gone away. My bloating has also subsided a little and my boobs have grown A LOT, which Im not complaining about haha. My hot flashes have got slightly worse but I had them anyway with my ADHD meds and POTs. I am very relieved that this has worked as it has given me my life back. Try and stick with it for 3-4 months before giving up, as im so glad I did.


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  1 day ago

Desogestrel pill  

I have mild adenomyosis and pcos, i wanted to try out a POP before a method with estrogen or inserting something I need a healthcare specialist to take out. In the end I couldn’t stick this out for the 3 months that they advise. Since starting I’ve had different side effects. The first week was bad reflux, the second week I had leg cramps, then I had 3 weeks of a constant thumping in my head with a headache that comes and goes, I was referred for an MRV and told to stop the pill. It’s been a week since I’ve stopped, every day the thumping has gotten quieter, no sudden “hits” in my head and today it’s finally gone. For whatever reason, it’s not for me. I will admit it did lighten my bleeding and it looked like it was on its way to stopping, but it never actually stopped completely before the headaches started.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
22 years old
🇬🇧 UK
  •  1 day ago

Desorex pill  

The first 2 years on this pill was fine, my moods were neutral and my periods stopped completely. However, this is my 3rd year using it and I’ve started growing darker facial hair on my chin and I’ve become more irritable with occasional breakthrough bleeding. Not sure if my body has just changed hormonally as I’ve grown older and doesn’t agree with Desorex anymore. My pharmacist recommended swapping to Noriday, so shall see how that goes and whether it improves my symptoms despite containing a higher amount of androgen than Desorex.


Somewhat negative mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
27 years old
🇬🇧 UK
  •  1 day ago

Slynd pill  

I was put on this after being diagnosed with PMDD. I was wary to go on a hormonal pill after having a horrible time when I was a teenager on the combined pill but this has been lifechanging. I was losing 2 weeks out of the month due to my mood, especially with my AUDHD too. I have now got them back. I feel so much more level and calm. For the first 3 months, I had vaginal dryness (which made sex painful), spotting and nausea but this has now completely gone away. My bloating has also subsided a little and my boobs have grown A LOT, which Im not complaining about haha. My hot flashes have got slightly worse but I had them anyway with my ADHD meds and POTs. I am very relieved that this has worked as it has given me my life back. Try and stick with it for 3-4 months before giving up, as im so glad I did.


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  1 day ago

Desogestrel pill  

I have mild adenomyosis and pcos, i wanted to try out a POP before a method with estrogen or inserting something I need a healthcare specialist to take out. In the end I couldn’t stick this out for the 3 months that they advise. Since starting I’ve had different side effects. The first week was bad reflux, the second week I had leg cramps, then I had 3 weeks of a constant thumping in my head with a headache that comes and goes, I was referred for an MRV and told to stop the pill. It’s been a week since I’ve stopped, every day the thumping has gotten quieter, no sudden “hits” in my head and today it’s finally gone. For whatever reason, it’s not for me. I will admit it did lighten my bleeding and it looked like it was on its way to stopping, but it never actually stopped completely before the headaches started.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
22 years old
🇬🇧 UK
  •  1 day ago

Desorex pill  

The first 2 years on this pill was fine, my moods were neutral and my periods stopped completely. However, this is my 3rd year using it and I’ve started growing darker facial hair on my chin and I’ve become more irritable with occasional breakthrough bleeding. Not sure if my body has just changed hormonally as I’ve grown older and doesn’t agree with Desorex anymore. My pharmacist recommended swapping to Noriday, so shall see how that goes and whether it improves my symptoms despite containing a higher amount of androgen than Desorex.


Somewhat negative mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
25 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

My side effects were all fine (basically non-existent) on Desogestrel besides very regular bleeding/spotting. The first 2-3 months were okay with a period-like bleed every 3 or 4 weeks with cramps too (although a lot less painful than my usual periods). But then the frequency increased. I tried to wait it out but after 7 months I was still experiencing spotting/bleeding every other week. Besides this I would’ve stayed on it and had no other problems. I’ve now changed to a combined pill which will hopefully make me bleed less.


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
38 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I was put on Desogestrel after being on the combined pill (Rigevidon) for many years, but I was suffering from migraines. I was on Desogestral for roughly 5 months, and didn't have a single migraine for the entire time. I also had started to get period like cramps when taking the combined pill, but not when I was actually on my period. This also completely vanished for me which was great. Unfortunately the one big down side for me, which has caused me to try another type of mini pill was that I ended up having more days than not where I was bleeding. It wasn't always a lot, but it was always on my mind, and I didn't know which days would be clear and which would be not clear. Some days the bleeding would fade out but it might start like I was on my period, causing me to use a pad just in case it carried on. I stuck with it as the mentioned pros were so good that I really wanted it to work for me but in the end I just couldn't stand having more days that I bled than not, and I never felt like I could relax.


Worse skin

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
18 years old
🇬🇧 UK
  •  2 weeks ago

Cerazette pill  

Ive been on this pill for over 5 months and I’m stopping. When I started about a month in I got horrible acne breakouts but I started using benzoyl peroxide and now it’s okay. I’ve had 3-4 periods and each one I’ve bled for weeks at a time so I am switching to a different one


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
37 years old
🇬🇧 UK
  •  3 weeks ago

Cerelle pill  

Would have been ok apart from the bile acid diarrhoea anytime I ate anything with fat in it! Thought I was lactose intolerant, stopped pill and suddenly I could eat dairy again! Weird, went on it again after having my son and the diarrhoea suddenly came back doctors said it couldn’t be the pill but I’m not on it now and after 3 weeks no more diarrhoea. Bit of an odd coincidence if it’s not the pill


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
37 years old
🇬🇧 UK
  •  3 weeks ago

Slynd pill  

Vaginal atrophy, painful sex, painful urination, extreme constipation, right sided abdominal pain that felt like being stabbed (caused by constipation), dizziness from low blood pressure, fainting, extreme anxiety, chest pain, high cortisol, insomnia, depression, crying a lot, depression, dry skin, thirst,


Very negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
37 years old
🇬🇧 UK
  •  3 weeks ago

Progestogen-only / Mini pill  

Vaginal atrophy, vulvar pain, painful sex zero libido, constipation so bad I went to a&e, caused horrible right sided abdominal pain, very dry skin, extreme anxiety, chest pain, insomnia, depression, low blood pressure, dizziness and fainting, over all sucked, took a few months before side effects hit


Very negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  6th Sep 26

Slynd pill  

I was taking Desogestrel for a year and was super happy with it no issues only a small three day period every few months everything seemed great. All of a sudden in the last month I have bled and bled even though I take my pill at the same time everyday. I was so upset and my mood went really low and I’m usually a very happy positively spirited person I have had no issues with mental health before. I believe it was because I was given a different brand of Desogestrel in my last 3 months it was called desorex (gold packaging) I have spoken to 3 girls at my work and they have all had the same problem absolutely fine until they started this brand of pill. The best advice I can give is stick to the brand you know and get on with! As the side effects and changes do differ so much even though they tell you Desogestrel tablets are all the same (they aren’t!!!) I have switched to slynd and my bleeding has completely gone, my mood is happy and normal and I feel healthy on it! I’m also glad to have a 4 day break to have a natural period as it gives me my cycle predictability back! It’s basically like a combined pill but no risk of blood clots which was my biggest worry! My skin is the same I just have small breakouts on my chin sometimes but that’s very normal to me, I don’t feel bloated and my weight has stayed the same. My boobs have definitely got bigger on this though could be temporary I’m not sure. Please try this pill if Desogestrel doesn’t work for you and you still want to be on a mini pill! Within 2 weeks it’s completely changed me making me happy and able to enjoy my sex life again without bleeding all the time! I will update this if anything changes :)


Very positive mood

2 helpful

2 comments

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