Injection vs Progestogen-only / Mini pill

Need help choosing? Speak to a doctor
Injection

Add your Injection review

Progestogen-only / Mini pill

£From £0.22/day

Overview

Rated 2.9

293 reviews

Every 2-3 months

Frequency

94% - 99+%

Effectiveness

None

Blood clot risk

Short term

Effect on fertility

Rated 2.7

1397 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Injection ingredients

Main hormones in Injection

progestogen


Progestogen-only / Mini pill ingredients

Main hormones in Progestogen-only / Mini pill

progestogen

What Lowdown reviewers say

32% somewhat negative

70% stopped periods

56% lost sex drive

49% gained weight

47% no impact on skin

Cycle return

43% don’t know impact

31% somewhat negative

44% stopped periods

49% lost sex drive

44% no impact

46% no impact on skin

Cycle return

38% don’t know impact

Benefits: What this contraceptive can help with

Endometriosis

Heavy periods

Period pain

Period pain

Try it now

Add your Injection review

Try it now

£From £0.22/day

Check out our latest reviews

Real life reviews from people like you

Injection reviews

293 reviews

Injection  
Used for 6 - 12 mo
25 years old
🇬🇧 UK
  •  2 days ago

Injection  

Side effects are bad

Read more

Worse skin

1 more effect

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
34 years old
🇬🇧 UK
  •  5 days ago

Depo-Provera injection  

All women should really do the research before starting this medication. I have read quite a few stories online of women who have felt the same. I have basically felt like a completely different person. I am near on the end of one injection and I will not be going back for another. It’s absolutely ruined my relationship with my partner. I’ve been absolutely horrible to him and it’s only now I’m starting to realise just what this injection did to me. Thank goodness he’s so understanding and helped me through it because I was literally horrendous. Literally a few days after I had it I was a different person, I hated him. Everything he done annoyed me, I was rude and hurtful and I couldn’t control it. I would snap in and out of moods so badly that we named the other “person” Patrica. He was constantly walking on egg shells as he never knew which version he would get. I am so upset that I have felt this way in the last few months. So much so I was having suicidal thoughts. I pray that anyone doesn’t risk it because it’s been 3 months of hell for us.


Very negative mood

2 more effects

0 helpful

0 comments

Injection  
Used for 18 mo - 3 yr
25 years old
🇬🇧 UK
  •  2 weeks ago

Depo-Provera injection  

This has been great for me helped regulate my moods no longer huge crashes i get around periods. Also it has completely stopped my periods which were heavy and painful, I get the occasional period pain leading up to when my injection is due but they are very very mild and don’t really effect me.


Very positive mood

1 more effect

0 helpful

0 comments

Injection  
Used for 6 - 12 mo
25 years old
🇬🇧 UK
  •  2 days ago

Injection  

Side effects are bad


Worse skin

1 more effect

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
34 years old
🇬🇧 UK
  •  5 days ago

Depo-Provera injection  

All women should really do the research before starting this medication. I have read quite a few stories online of women who have felt the same. I have basically felt like a completely different person. I am near on the end of one injection and I will not be going back for another. It’s absolutely ruined my relationship with my partner. I’ve been absolutely horrible to him and it’s only now I’m starting to realise just what this injection did to me. Thank goodness he’s so understanding and helped me through it because I was literally horrendous. Literally a few days after I had it I was a different person, I hated him. Everything he done annoyed me, I was rude and hurtful and I couldn’t control it. I would snap in and out of moods so badly that we named the other “person” Patrica. He was constantly walking on egg shells as he never knew which version he would get. I am so upset that I have felt this way in the last few months. So much so I was having suicidal thoughts. I pray that anyone doesn’t risk it because it’s been 3 months of hell for us.


Very negative mood

2 more effects

0 helpful

0 comments

Injection  
Used for 18 mo - 3 yr
25 years old
🇬🇧 UK
  •  2 weeks ago

Depo-Provera injection  

This has been great for me helped regulate my moods no longer huge crashes i get around periods. Also it has completely stopped my periods which were heavy and painful, I get the occasional period pain leading up to when my injection is due but they are very very mild and don’t really effect me.


Very positive mood

1 more effect

0 helpful

0 comments


Progestogen-only / Mini pill reviews

1397 reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  1 day ago

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  6 days ago

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
22 years old
🇬🇧 UK
  •  1 week ago

Cerelle pill  

Got pregnant on it because I wasn’t taking it properly, since having my son and ensuring to take it regularly I have had no issues


Improved skin

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  1 day ago

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  6 days ago

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
22 years old
🇬🇧 UK
  •  1 week ago

Cerelle pill  

Got pregnant on it because I wasn’t taking it properly, since having my son and ensuring to take it regularly I have had no issues


Improved skin

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
35 years old
🇬🇧 UK
  •  2 weeks ago

Cerazette pill  

I really wanted to write about my positive experience as most people write reviews when they have a negative experience, for me the Cerazette has been really good, it improved my feeling of being in balance and lessened mood swings, it did not effect my libido, in fact in the beginning I noticed a higher libido, but most importantly I suffer from migraines with aura and since I started taking this a month ago I didn’t have an intense migraine, just one or two mild days and I normally have 2/3 days per week so in a month 8 at least. The only negative things are not too bad: I have very tender breasts which became a bit bigger but I heard this might go away after 3 months or so and I got a little bit of acne but nothing too crazy and this also usually settles after taking it consistently for a few month. All in all for me it’s truly been life changing.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
21 years old
🇬🇧 UK
  •  3 weeks ago

Desogestrel pill  

The first 3-5 months were a bit rough, having sex would cause me to get a period and sometimes was painful. I also was definitely more emotional than before. It all calms down over time, I’ve been on it for almost 3 years now and it was the best decision i get very occasionally spotting and cramps if i miss a pill or two but overall I like it


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  3 weeks ago

Zelleta pill  

Went on the mini pill at 16 for 3 years. The first 9 months I bled pretty constantly (no cramps at least) then bled randomly most months. Bleeding was usually light and unpainful. My mood swings were awful and my skin broke out and got so much worse (quite discouraging after being on accutane). Didn’t notice any weight gain or other side effects. I later changed to the combined pill to try and help my skin but this caused other issues (high blood pressure, recurrent yeast infections) so last week I got the copper IUD! Would not recommend. As a 16 year old the doctor did not give me much information about my choice and the impact it would have on me. She just said “if you trust your boyfriend you don’t need to use condoms now” …


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  3 weeks ago

Desogestrel pill  

I was on Microgynon 30 for almost 8 years and I never had any issues! I changed 3 months ago to the progesterone only pill (Desogesterel) due to my friend getting a blood clot from microgynon, and within a month I began getting spots all over my jawline! I have now had constant spots for 2 months. I also have breakthrough bleeding which I never had on Microgynon. I will be heading back to the pharmacy to discuss my options


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
38 years old
🇬🇧 UK
  •  1 month ago

Slynd pill  

I started using slynd around 6 months ago for period control due to heavy flow and pain Initially I felt optimistic I never took the placebo green pills as I was on tricycling method I still had a period every month with ovarian pain I had a 4 week spotting episode I’ve had 3 utis which I never had in my life every month for the last 3 My sex drive dropped off the earth and there was none My mood went from frantic cycling cleaning the house and obsessing over things to emotionally crying before feeling stupid and back to normal The biggest thing for me was hair loss at least half my hair fell Out in week one I stayed commuted thinking it would get better until bald patches started to appear in month 5 that’s when I jd enough I also had graphic nightmares waking up with sweating so bad my sheets were soaked Since finished this pill I feel like I’m getting back to me with no mood swings or low mood I am 38 and maybe I needed some Oestrogen to balance it out this pill was not for me


Very negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
25 years old
🇬🇧 UK
  •  6th Jun 25

Cerazette pill  

I swapped from the combined pill to Cerazette because I was having anxiety, dizziness and low libido. These have both improved since changing. The most annoying thing has been inconsistent bleeding and spotting. I won’t bleed for 3 months then will have spotting out of nowhere for 3 weeks. I have also got acne on my chin which I didn’t have before. Overall though these extra inconveniences have far outweighed the reduced anxiety, dizziness and libido issues.


Very positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
43 years old
🇬🇧 UK
  •  6th Jun 25

Desogestrel pill  

I’m very satisfied with the pill. I only been taking it for few weeks but my mental health improved so much ! I can’t actually believe it. I used to suffer mood swings due to hormonal fluctuations . None of this is happening . Very happy. No side effects either


Very positive mood

1 more effect

0 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Injection with other contraceptives

Order online

Order online now

Use our online prescription in under 5 mins

  • No GP appointment needed

  • Free standard delivery

Speak to a doctor

Not sure yet? Speak to a doctor

Schedule an appointment now

87% of women are happier with their contraceptive choice after speaking with one of The Lowdown's doctors

The Lowdown Footer

Women's health, reviewed.

Get the best women’s health info in your inbox

You are signing up to receive The Lowdown's latest findings and news in women's health. Your data will be used in accordance with our Privacy & Cookie policy

Built by doctors and experts

Our tools are made by medical professionals for your peace of mind

Our website uses affiliate links and we may earn a small commission if you click on them