Injection vs Progestogen-only / Mini pill

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Injection

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Progestogen-only / Mini pill

£From £0.22/day

Overview

Rated 2.9

311 reviews

Every 2-3 months

Frequency

94% - 99+%

Effectiveness

None

Blood clot risk

Short term

Effect on fertility

Rated 2.7

1493 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Injection ingredients

Main hormones in Injection

progestogen


Progestogen-only / Mini pill ingredients

Main hormones in Progestogen-only / Mini pill

progestogen

What Lowdown reviewers say

31% somewhat negative

70% stopped periods

57% lost sex drive

48% gained weight

47% no impact on skin

Cycle return

43% don’t know impact

31% somewhat negative

44% stopped periods

49% lost sex drive

44% no impact

46% no impact on skin

Cycle return

39% don’t know impact

Benefits: What this contraceptive can help with

Endometriosis

Heavy periods

Period pain

Period pain

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£From £0.22/day

Check out our latest reviews

Real life reviews from people like you

Injection reviews

311 reviews

Injection  
Used for 1 - 3 mo
27 years old
🇬🇧 UK
  •  3 days ago

Depo-Provera injection  

First 3 weeks were fine, I spent first 3 days filled with rage and nausea and a few headaches but fine. First expected period rolled around at 3 weeks in and didn't stop, like at all (day 77 as I write this). About 6 weeks in my mood crashed. As someone who has previously had mental health problems, I was incredibly apprehensive about going on any kind of hormonal birth control because I was scared of side effects. But in order to get my tubes tied, my doctors wanted to see me try this first and everyone reassured me that I was just being paranoid and it wouldn't be as bad as I imagined. Unfortunately it was worse than I imagined. I spent 4 weeks getting progressively more suicidal until I finally went to the doctors (which was its own story) but had to take three Valium a day in order to function and go to work. At the time of writing, I'm 2 weeks out of the 12-week expected window, still bleeding and still suffering mentally but less so and more manageably. This experience has put me off trying any other form of birth control. I had done this to try and reduce PMS symptoms and wish I never had. I was also recommended the mirena coil but didn't like the idea of having to have it inserted or removed if things went wrong/justify myself to a doctor

Read more

Very negative mood

1 more effect

0 helpful

0 comments

Injection  
Used for 6 - 12 mo
21 years old
🇬🇧 UK
  •  1 month ago

Depo-Provera injection  

I went on the depo injection due to the mini pill making my IBS constipation symptoms worse and the doctor saying this would be better. For first 6 months, no side effects. It did level out my moods and constipation, but it gave me vaginal dryness and a loss of sex drive after 9 months of being on it.


Somewhat positive mood

3 more effects

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  5th May 26

Depo-Provera injection  

I got with a new partner a few years back and gave this ago as I wanted something I didn’t need to remember to take. I gained weight fast, I had mood changes, my skin broke out badly, my periods were heavier than before. I only ever had one injection then stopped as I no longer needed it and I didn’t like how it made me feel. Unfortunately I had a rare side effect where it stopped my periods/ovulation all together for 12 months I was referred to gynaecology at 6 months and luckily after all the scans everything was normal and by month 12 my cycle returned without needing to be medically induced. This is not a horror story but important that you could react the same or if you are reacting the same please get referred to gynaecology and hopefully your periods will return 🤍


Somewhat negative mood

2 more effects

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
27 years old
🇬🇧 UK
  •  3 days ago

Depo-Provera injection  

First 3 weeks were fine, I spent first 3 days filled with rage and nausea and a few headaches but fine. First expected period rolled around at 3 weeks in and didn't stop, like at all (day 77 as I write this). About 6 weeks in my mood crashed. As someone who has previously had mental health problems, I was incredibly apprehensive about going on any kind of hormonal birth control because I was scared of side effects. But in order to get my tubes tied, my doctors wanted to see me try this first and everyone reassured me that I was just being paranoid and it wouldn't be as bad as I imagined. Unfortunately it was worse than I imagined. I spent 4 weeks getting progressively more suicidal until I finally went to the doctors (which was its own story) but had to take three Valium a day in order to function and go to work. At the time of writing, I'm 2 weeks out of the 12-week expected window, still bleeding and still suffering mentally but less so and more manageably. This experience has put me off trying any other form of birth control. I had done this to try and reduce PMS symptoms and wish I never had. I was also recommended the mirena coil but didn't like the idea of having to have it inserted or removed if things went wrong/justify myself to a doctor


Very negative mood

1 more effect

0 helpful

0 comments

Injection  
Used for 6 - 12 mo
21 years old
🇬🇧 UK
  •  1 month ago

Depo-Provera injection  

I went on the depo injection due to the mini pill making my IBS constipation symptoms worse and the doctor saying this would be better. For first 6 months, no side effects. It did level out my moods and constipation, but it gave me vaginal dryness and a loss of sex drive after 9 months of being on it.


Somewhat positive mood

3 more effects

0 helpful

0 comments

Injection  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  5th May 26

Depo-Provera injection  

I got with a new partner a few years back and gave this ago as I wanted something I didn’t need to remember to take. I gained weight fast, I had mood changes, my skin broke out badly, my periods were heavier than before. I only ever had one injection then stopped as I no longer needed it and I didn’t like how it made me feel. Unfortunately I had a rare side effect where it stopped my periods/ovulation all together for 12 months I was referred to gynaecology at 6 months and luckily after all the scans everything was normal and by month 12 my cycle returned without needing to be medically induced. This is not a horror story but important that you could react the same or if you are reacting the same please get referred to gynaecology and hopefully your periods will return 🤍


Somewhat negative mood

2 more effects

0 helpful

0 comments


Progestogen-only / Mini pill reviews

1493 reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
27 years old
🇬🇧 UK
  •  today

Zelleta pill  

Feel like the mini pill has levelled out my mood after years of going literally crazy 1-2 days before my period. Having no periods is a welcome relief but I have experienced a slight drop in libido and some dryness which isn’t ideal.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  2 weeks ago

Slynd pill  

Slynd started off great no period was a bonus, water retention went down. Then after 2 months it made me very irritable and my mood very very low. Within a week of stopping both returned to normal.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
22 years old
🇬🇧 UK
  •  2 weeks ago

Cerazette pill  

went on cerazette after trying out microgynon30ED and noriday (which both caused frequent irregular bleeding). My GP told me cerazette was fantastic for people who experience frequent bleeding on other mini-pills and often their periods stop. i started it back in late september 2025, and experienced bleeding every second week. fine, i thought, it’s just my body getting used to it! by november i was having just one period a month again! yay!! this was short lived however, as by december i was back to having it every 2nd week. in january i bled for 25 days straight. i was told that the first 3-5 months are expected to see changes in bleeding, so i stuck it out a bit longer. unfortunately the bleeding never stopped, and i continued to get my period now every week and a half, or sometimes even more frequently with only 3 days break in between cycles. :( it’s end of may now and have been on cerazette for 9 months. i am still bleeding every week and a half and honestly im sick of it. i have stopped taking cerazette now. hopefully there’s another one out there for me :(


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
27 years old
🇬🇧 UK
  •  today

Zelleta pill  

Feel like the mini pill has levelled out my mood after years of going literally crazy 1-2 days before my period. Having no periods is a welcome relief but I have experienced a slight drop in libido and some dryness which isn’t ideal.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
32 years old
🇬🇧 UK
  •  2 weeks ago

Slynd pill  

Slynd started off great no period was a bonus, water retention went down. Then after 2 months it made me very irritable and my mood very very low. Within a week of stopping both returned to normal.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
22 years old
🇬🇧 UK
  •  2 weeks ago

Cerazette pill  

went on cerazette after trying out microgynon30ED and noriday (which both caused frequent irregular bleeding). My GP told me cerazette was fantastic for people who experience frequent bleeding on other mini-pills and often their periods stop. i started it back in late september 2025, and experienced bleeding every second week. fine, i thought, it’s just my body getting used to it! by november i was having just one period a month again! yay!! this was short lived however, as by december i was back to having it every 2nd week. in january i bled for 25 days straight. i was told that the first 3-5 months are expected to see changes in bleeding, so i stuck it out a bit longer. unfortunately the bleeding never stopped, and i continued to get my period now every week and a half, or sometimes even more frequently with only 3 days break in between cycles. :( it’s end of may now and have been on cerazette for 9 months. i am still bleeding every week and a half and honestly im sick of it. i have stopped taking cerazette now. hopefully there’s another one out there for me :(


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
38 years old
🇬🇧 UK
  •  1 month ago

Zelleta pill  

I was on the depo shot for 22 years and really started to worry about my bone density as my mother has osteoporosis and I was also struggling to inject in certain bits of my stomach from scar nodules. So I swapped to the mini pill as its the same but with less side effects. I originally came to this site to read the reviews and as usual, people always tend to leave a review for the negatives. I can honestly say Ive had absolutely no side effects, my period still hasn't returned after being on the shot and I've actually lost weight. Hopefully someone needs to read this.


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
24 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

Not a good experience, lots of weight gain, more emotional/moody. cant wear contacts anymore


Somewhat negative mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
20 years old
🇬🇧 UK
  •  1 month ago

Cerazette pill  

I was a bit more emotional my first 1-2 months on it but then I was fine. Completely took away my debilitating period pains, I get one very mild cramp about once a month and that's it. No side effects except for some constant spotting. I Googled it and started taking 2 pills instead of 1 and the spotting has since stopped. My weight, sex drive, skin, and mood are unaffected as of now (8 months of taking it daily)


Lost weight

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  10th May 26

Slynd pill  

I'm in months 2 and hoping things get a little better. Pro: No periods or period pain/endo pain! (HURRAY) And no weightgain (which i had on another pill) Con: I'm feeling down, sleep bad, hair loss, forgetful, spotting, BV, vaginal dryness, heart pains and rising anxiety. I want to give it a month extra or so but the side effects are getting me down. This is the 2nd pill I've tried this year. The first one was a combined pill but made my uterine lining super thick and that gave me massive cramps and hurt. So let's see but kinda sceptical.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
31 years old
🇬🇧 UK
  •  8th May 26

Slynd pill  

I love this pill. I was struggling with mood and physical symptoms around pms, I have tried several oral contraceptives intermittently over the last 15 years but had other side effects to them, I was using a Kyleena coil which worked really well for contraception and period control but as this did not stop me ovulating, PMS became my main concern. I tried Slynd when it became available in the UK and I love it. My cyclical mood, bloating and skin issues have basically completely resolved and the longer missed pill window works much better for me.


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
18 years old
🇬🇧 UK
  •  7th May 26

Zelleta pill  

this was my first contraception ever. i had read up on it so had an idea of what to expect but after a week of taking it i could already see the affect it was having on my body. i was easily gaining much more weight than i would when eating the same foods, same amount of foods. i was never one to have spots and noticed my skin getting loads around my forehead and cheeks. my mood was terrible, always angry and irritated causing a lot of arguments between me and my boyfriend. decreased sex drive. i decided to stop it as i just didn’t feel like myself anymore, im 4 days off it and im feeling a lot better than i was taking it.


Very negative mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
29 years old
🇬🇧 UK
  •  5th May 26

Desogestrel pill  

I’d been off contraception for years and I wanted to go back on it as in a relationship and not TTC just yet. So far it seems to be okay th first 2 months was where i experienced most my symptoms mainly have settled sort from sex drive, headaches, no periods they still exist on month 5.


Somewhat negative mood

2 more effects

0 helpful

0 comments

Contraceptive alternatives and comparisons

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