Gynefix vs Combined pill

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Gynefix

Add your Gynefix review

Combined pill

£From £0.16/day

Overview

Rated 4.4

11 reviews

5 years

Frequency

Over 99%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.8

2541 reviews

Daily

Frequency

91% - 99+%

Effectiveness

Increased

Blood clot risk

None

Effect on fertility

Gynefix ingredients

The GyneFix is made of a non-biodegradable suture thread made of surgical 00 monofilament polypropylene (AKA a type of plastic) on which six copper tubes are threaded

Combined pill ingredients

Main hormones in Combined pill

progestogen

oestrogen

What Lowdown reviewers say

55% no impact on mood

36% regular periods

82% no impact

91% no impact

82% no impact on skin

Cycle return

Not enough data to say

32% somewhat negative

48% lighter periods

46% lost sex drive

48% no impact

44% improved skin

Cycle return

36% don’t know impact

Benefits: What this contraceptive can help with

There are no benefits that are recognised in scientific research or guidelines for this contraceptive

Acne or bad skin

Heavy periods

PMS and PMDD

PCOS symptoms

Period pain

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£From £0.16/day

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Real life reviews from people like you

Gynefix reviews

11 reviews

Gynefix  
Used for 1 - 3 mo
30 years old
🇬🇧 UK
  •  1 month ago

Gynefix  

I got my gynefix mini online and had it inserted at the John Hunter clinic in London. I had paraguard before which gave me terrible cramps and incredibly heavy periods: I had Jaydess for 3 years which gave low but manageable mood but I started having terrible back pains either it. Once I had it removed, back pains stopped. I didn’t use anything for a while and then tried the implant, which was awful! It gave me terrible mood swings and anger! Went back to jaydess and back pains returned and low mood. I started looking for other options and found gynefix and I am so glad I did! Insertion was painful and my periods are significantly heavier but nothing I can’t live with. No back-pains, no horrible craps and no mood effects! Thank you whoever created this! I really forget it is there and only sometimes can slightly feel it, but this is by far the best contraception I’ve tried! It was hard to find a dr to get it fitted and I had to order it myself as NHS don’t supply it, but worth it!

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Very positive mood

0 helpful

0 comments

Gynefix  
Used for 12 - 18 mo
23 years old
🇬🇧 UK
  •  4th Jan 25

Gynefix  

Got one at mortimer market in 2023 and other than a slight increase in discharge (normal discharge), which to be honest I don't think is related to the gynefix, I have had an amazing experience with the gynefix, I just wish it lasted longer than 5 years! Insertion was very smooth; uncomfortable/painful for sure but nothing terrible and not the worst pain of my life, I was able to walk home after the procedure. Had spotting / light bleeding throughout my cycle for maybe a month or two, and I remember having spotting for a few months, but honestly nothing crazy or super annoying. My period was a bit heavier for a few months after insertion but now it is back to my normal (I had light, minimal pain periods before the gynefix for context!). I love it and wish it was more available in the UK, fear that when I need it out I wont be able to get it on the NHS and I can't see myself wanting any other contraception.


Very positive mood

0 helpful

0 comments

Gynefix  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  16th Sep 24

Gynefix  

The insertion and week after insertion was incredibly painful, I had cramps running from my back to my uterus and down my thighs and I was bed bound. My periods became ridiculously heavy and the period cramps were incredibly intense. In the end, one day my period pain was so intense I pulled the IUD out myself at home. Pulling it out didn't hurt at all and the pain stopped immediately.


Very negative mood

0 helpful

0 comments

Gynefix  
Used for 1 - 3 mo
30 years old
🇬🇧 UK
  •  1 month ago

Gynefix  

I got my gynefix mini online and had it inserted at the John Hunter clinic in London. I had paraguard before which gave me terrible cramps and incredibly heavy periods: I had Jaydess for 3 years which gave low but manageable mood but I started having terrible back pains either it. Once I had it removed, back pains stopped. I didn’t use anything for a while and then tried the implant, which was awful! It gave me terrible mood swings and anger! Went back to jaydess and back pains returned and low mood. I started looking for other options and found gynefix and I am so glad I did! Insertion was painful and my periods are significantly heavier but nothing I can’t live with. No back-pains, no horrible craps and no mood effects! Thank you whoever created this! I really forget it is there and only sometimes can slightly feel it, but this is by far the best contraception I’ve tried! It was hard to find a dr to get it fitted and I had to order it myself as NHS don’t supply it, but worth it!


Very positive mood

0 helpful

0 comments

Gynefix  
Used for 12 - 18 mo
23 years old
🇬🇧 UK
  •  4th Jan 25

Gynefix  

Got one at mortimer market in 2023 and other than a slight increase in discharge (normal discharge), which to be honest I don't think is related to the gynefix, I have had an amazing experience with the gynefix, I just wish it lasted longer than 5 years! Insertion was very smooth; uncomfortable/painful for sure but nothing terrible and not the worst pain of my life, I was able to walk home after the procedure. Had spotting / light bleeding throughout my cycle for maybe a month or two, and I remember having spotting for a few months, but honestly nothing crazy or super annoying. My period was a bit heavier for a few months after insertion but now it is back to my normal (I had light, minimal pain periods before the gynefix for context!). I love it and wish it was more available in the UK, fear that when I need it out I wont be able to get it on the NHS and I can't see myself wanting any other contraception.


Very positive mood

0 helpful

0 comments

Gynefix  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  16th Sep 24

Gynefix  

The insertion and week after insertion was incredibly painful, I had cramps running from my back to my uterus and down my thighs and I was bed bound. My periods became ridiculously heavy and the period cramps were incredibly intense. In the end, one day my period pain was so intense I pulled the IUD out myself at home. Pulling it out didn't hurt at all and the pain stopped immediately.


Very negative mood

0 helpful

0 comments


Combined pill reviews

2541 reviews

Combined pill  
Used for 12 - 18 mo
19 years old
🇬🇧 UK
  •  3 days ago

Mercilon pill  

Good pill, not a lot of mood changes however when I took a break from it for a few months my mood improved so much that I almost didn’t go back. This is my second time trying it so I hope it doesn’t affect me too much


Somewhat negative mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  4 days ago

Rigevidon  

Don't get this contraception if you want to keep your good mental health. It almost ruined my relationship, I turned into a complete monster. The short periods and the clear skin was nice but it really jeopardised my relationship and ruined my mental health. Coming off was the best thing I could've ever done for myself.


Very negative mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
21 years old
🇬🇧 UK
  •  5 days ago

Dretine pill  

I was initially prescribed Yasmin to help with low moods/depression before my period. However, I was then switched to Dretine without explanation and told it was the same as Yasmin. Since taking it, my mood has been all over the place- very sensitive, sad, depression-like feelings, anxiety/overthinking a lot more than usual. I'm switching back to Yasmin as I had a positive experience with it in the first place.


Very negative mood

0 helpful

0 comments

Combined pill  
Used for 12 - 18 mo
19 years old
🇬🇧 UK
  •  3 days ago

Mercilon pill  

Good pill, not a lot of mood changes however when I took a break from it for a few months my mood improved so much that I almost didn’t go back. This is my second time trying it so I hope it doesn’t affect me too much


Somewhat negative mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  4 days ago

Rigevidon  

Don't get this contraception if you want to keep your good mental health. It almost ruined my relationship, I turned into a complete monster. The short periods and the clear skin was nice but it really jeopardised my relationship and ruined my mental health. Coming off was the best thing I could've ever done for myself.


Very negative mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
21 years old
🇬🇧 UK
  •  5 days ago

Dretine pill  

I was initially prescribed Yasmin to help with low moods/depression before my period. However, I was then switched to Dretine without explanation and told it was the same as Yasmin. Since taking it, my mood has been all over the place- very sensitive, sad, depression-like feelings, anxiety/overthinking a lot more than usual. I'm switching back to Yasmin as I had a positive experience with it in the first place.


Very negative mood

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
31 years old
🇬🇧 UK
  •  5 days ago

Yasmin pill  

Made the mistake of changing to the Progestogen-only/mini pill 'Desogestrel' August 2023. Caused me to be deeply depressed while on it, and I also experienced serious gastro-related episodes (twice) where I woke in the middle of the night and nearly fainted while on the toilet, with bad stomach aches then following for the next week or so. More relevant now, that pill also caused my skin to break out badly, the worse I'd ever had it (being a person before who had ever only experienced a few spots here and there). These spots were almost always appearing around my mouth around. Once I realised this pill was causing all of these symptoms, I came straight off and was advised to go back on a previous combined I'd been on for years. Depression and the gastro episodes cleared up, but the acne did not. I then experimented with coming off hormonal contraception altogether, hoping my skin would go back to normal. It did not, so I consulted the GP about a pill that was known for clearing up acne effectively. She put me on Yasmin, which I started 25/1/25. In the first month I did experience some feelings of nausea that I have heard people talk about, but that was only in the first few weeks on it. Also had one headache that went on for a couple of days, which is unusual for me, however I had also read that was common and I haven't experienced one since. Regarding my skin, it seemed to get a little worse for the first month, plus maybe a couple of weeks. I am now almost 2 months on this pill (having taken one 4 day break after my first pack, and now in the process of taking 3 packs consecutively) and I am hopeful that the frequency of spots is steadily going down. I also worked with ChatGPT (my very own virtual PA, haha) to create an oil-reducing skincare routine, so that might also be helping. Another positive is that my breasts have gotten larger, but no weight gain other than that! Will update again when I'm at 3 months on.


Top side effects not reported

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
18 years old
🇬🇧 UK
  •  6 days ago

Levest pill  

Went on this pill to try and ease my intense cramps, but it made my periods much much heavier and I’m not sure its worth it.


Worse skin

2 more effects

0 helpful

0 comments

Combined pill  
Used for 3 - 5 yr
25 years old
🇬🇧 UK
  •  1 week ago

Millinette 30/75 pill  

Little to no side effects, I am glad I am in this pill


Improved skin

0 helpful

0 comments

Combined pill  
Used for 3 - 6 mo
21 years old
🇬🇧 UK
  •  2 weeks ago

Yacella pill  

Prescribed for pcos. I no longer have pelvic and abdominal pain :) and my mood is better as I do not have pms anymore, it helped my hormonal alopecia. I also notice my face looks different like it’s less chubby or puffy. The negatives are it gave me a phase of acne which eventually cleared and headaches, the first break I took on it was a really bad headache where I had to stay in a lot so I could be in dark to relieve the pain.


Somewhat positive mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 12 - 18 mo
27 years old
🇬🇧 UK
  •  2 weeks ago

Millinette 30/75 pill  

Positives - Balanced mood, bigger boobs, great skin and generally little to no side effects Negatives - Bad nausea once you first start taking it (1-2 weeks worth), severe headaches on the pill break I went on this pill as had heard it may help my PMS symptoms. The week before my period I was experiencing low moods and emotional sensitivity. This pill CHANGED that. I now have a balanced mood throughout the whole month. The only time I notice pms like symptoms is when I have taken a few packets back to back - your body defo tells you you need a pill break. Overall, would recommend


Very positive mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 3 - 6 mo
19 years old
🇬🇧 UK
  •  3 weeks ago

Rigevidon  

I started taking Regivedon combined pill in order to have periods as a peace of mind I wasn’t pregnant, as my mini pill I was taking (cerazette) stopped them. The first week was a massive rollercoaster of emotions and by the end of the week I was exhausted, but this was fairly normal (not usually this extreme) as my body has to adapt. Afterwards it was a general downward slope of mood swings with very negative episodes lasting longer and longer and eventually came off it after realising. I felt like a weight had come off. Everyone is different though, they say mini pill affects mood more but for me combined was hell! Pre warning though I have had past experience with very low mood and depression so I am probably more susceptible.


Very negative mood

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
30 years old
🇬🇧 UK
  •  3 weeks ago

Zoely pill  

I was on this pill just shy of a month. I was bloating on the first day of use. I noticed the first week my mental state was horrible very agitated, flat and no energy. I did notice after the first few weeks my skin was definitely clearing up. I get hormonal acne. I had reduced hair loss (from endometriosis) and no ovulation pain. 3rd week in I started to get a sharp pain in the calf. Subsided then came back worse. So decided to stop taking it all together because leg pain wasn't worth the possibility of a blood clot. Three days off the pill the leg pain completely disappeared. Definitely was not the pill for me. Cons- Low mood Low sex drive Joint pain Sore lower back Constant bloating Extreme calf pain Insomnia Nausea Chest hypertension Pros- Clearer skin Less hair loss No ovulation pain


Very negative mood

2 more effects

0 helpful

0 comments

Contraceptive alternatives and comparisons

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