Desomono pill vs Desogestrel pill

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Desomono pill

£From £0.18/day

Desogestrel pill

£From £0.20/day

Overview

Rated 2.1

19 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.7

400 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Desomono pill ingredients

Main hormones in Desomono pill

Less-Androgenic progestogen


Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen

What Lowdown reviewers say

32% no impact on mood

58% irregular periods

42% lost sex drive

53% no impact

25% improved skin

Cycle return

100% in 1 month

33% somewhat negative

43% stopped periods

52% lost sex drive

44% no impact

47% no impact on skin

Cycle return

41% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

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£From £0.18/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Desomono pill reviews

19 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
31 years old
🇬🇧 UK
  •  14th May 25

Desomono pill  

I started the generic name for it: Desogestrel, I got given the brand Desomono once too, but most of the time the generic name. On it for 6 months, coming to 7. It's been great in many ways I wanted. I was sacred my mental health would be affected or I'd get acne. I monitored but I didn't get any negative or increasing mental health issues. No acne. Maybe a bit of hair thinning but I have that problem from before. A little weight gain but it could be new marriage fat. My main concern which is annoying as I was happy otherwise was that after 15 days of taking it, I was bleeding non stop till this day, bloody discharge or just blood, not lots like period but annoying as I wore pads for the bit of blood so it doesn't go on the side of my knickers. I'm started to feel a bit itchy around my vulva but that could be due to constant wear of pads. My breasts are starting to feel a little tendor and I think I feel a little less lubricated down there during intimacy. I'll be trying the combined pill next month because of the above mainly the bleeding. I'm gonna try Levest.. I hope it doesn't play with my mind!!

Read more

Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
Lowdown user
🇬🇧 UK
  •  29th Jan 24

Desomono pill  

This is my favourite contraception. Other brands make my mental health so bad this doesn't. Period cramps can be bad but that's about it. Highly recommend


Very positive mood

1 more effect

5 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
Lowdown user
🇬🇧 UK
  •  19th Dec 23

Desomono pill  

This was the 1st contraception I ever tried and I went on this pill for 2 reasons: The 1st was for cramps and the 2nd was for a contraception which I used alongside condoms. When I started this pill I was on my period/experienced spotting for 140days from May (when I started the pill) to December. However, I did not experience cramps so I was happy to continue with this pill as the period was very light. After this I got my period about every 6weeks and started to get mild cramps but would reduce with paracetamol. After about 18 months of being on this pill I started to experience cramps again. My period was been dreadful. I’ve been on my period for 2weeks now with cramps and heavier bleeding than usual. I’m really tired and run down due to it all and absolutely hate it. A new doctor informed me that this was not the best pill to go on if I don’t have any underlying health problems i.e. A risk of clots. I had no other side effects on this pill so I think it is a good option if you don’t experience cramps and are looking for a contraceptive with less hormones as my friend has had a good experience on it. However it’s definitely not for me and I’m going to change asap.


Somewhat negative mood

1 more effect

4 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
31 years old
🇬🇧 UK
  •  14th May 25

Desomono pill  

I started the generic name for it: Desogestrel, I got given the brand Desomono once too, but most of the time the generic name. On it for 6 months, coming to 7. It's been great in many ways I wanted. I was sacred my mental health would be affected or I'd get acne. I monitored but I didn't get any negative or increasing mental health issues. No acne. Maybe a bit of hair thinning but I have that problem from before. A little weight gain but it could be new marriage fat. My main concern which is annoying as I was happy otherwise was that after 15 days of taking it, I was bleeding non stop till this day, bloody discharge or just blood, not lots like period but annoying as I wore pads for the bit of blood so it doesn't go on the side of my knickers. I'm started to feel a bit itchy around my vulva but that could be due to constant wear of pads. My breasts are starting to feel a little tendor and I think I feel a little less lubricated down there during intimacy. I'll be trying the combined pill next month because of the above mainly the bleeding. I'm gonna try Levest.. I hope it doesn't play with my mind!!


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
Lowdown user
🇬🇧 UK
  •  29th Jan 24

Desomono pill  

This is my favourite contraception. Other brands make my mental health so bad this doesn't. Period cramps can be bad but that's about it. Highly recommend


Very positive mood

1 more effect

5 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
Lowdown user
🇬🇧 UK
  •  19th Dec 23

Desomono pill  

This was the 1st contraception I ever tried and I went on this pill for 2 reasons: The 1st was for cramps and the 2nd was for a contraception which I used alongside condoms. When I started this pill I was on my period/experienced spotting for 140days from May (when I started the pill) to December. However, I did not experience cramps so I was happy to continue with this pill as the period was very light. After this I got my period about every 6weeks and started to get mild cramps but would reduce with paracetamol. After about 18 months of being on this pill I started to experience cramps again. My period was been dreadful. I’ve been on my period for 2weeks now with cramps and heavier bleeding than usual. I’m really tired and run down due to it all and absolutely hate it. A new doctor informed me that this was not the best pill to go on if I don’t have any underlying health problems i.e. A risk of clots. I had no other side effects on this pill so I think it is a good option if you don’t experience cramps and are looking for a contraceptive with less hormones as my friend has had a good experience on it. However it’s definitely not for me and I’m going to change asap.


Somewhat negative mood

1 more effect

4 helpful

0 comments


Desogestrel pill reviews

400 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
30 years old
🇬🇧 UK
  •  1 day ago

Desogestrel pill  

It feels nice not having a period. But I’ve noticed I’ve become more spotty , I sweat more also & get thrush


Somewhat positive mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
21 years old
🇬🇧 UK
  •  6 days ago

Desogestrel pill  

I spotted for 3 months straight, but then stopped periods all together. I felt a bit sick after taking it, so i should’ve probably taken it after food or at night but i took in the morning. I feel like it made me quite anxious, but i’ve been off it for two years and still have anxiety problems so i’m not 100% whether it’s related! The sickness feeling made me feel quite nervous i think. No other side effects.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
20 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

Ok but not a fan of the hair loss and continuous spotting


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
30 years old
🇬🇧 UK
  •  1 day ago

Desogestrel pill  

It feels nice not having a period. But I’ve noticed I’ve become more spotty , I sweat more also & get thrush


Somewhat positive mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
21 years old
🇬🇧 UK
  •  6 days ago

Desogestrel pill  

I spotted for 3 months straight, but then stopped periods all together. I felt a bit sick after taking it, so i should’ve probably taken it after food or at night but i took in the morning. I feel like it made me quite anxious, but i’ve been off it for two years and still have anxiety problems so i’m not 100% whether it’s related! The sickness feeling made me feel quite nervous i think. No other side effects.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
20 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

Ok but not a fan of the hair loss and continuous spotting


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

i’m not sure if it is normal but i have been on this pill for 3 months. a week into the taking the pill my period finally came back after around 100 days. since then ive had very irregular periods often bleeding for extended periods of time and also spotting more often with the periods being closer together. i have also experienced much more mood changes as i have felt somewhat more depressed on this pill. this might just be my experience and might also be influenced by the fact i am still going through pubity as i’m 16 yet i still can’t stop thinking that something is wrong .


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
24 years old
🇬🇧 UK
  •  3 weeks ago

Desogestrel pill  

I’m was happy with the mini pill as I took it while breastfeeding my son, however as soon as I weaned him my periods came back but they were all over the place. I bled for nearly 2 weeks straight then it finally stopped, but only for 3 days then it started again. If it wasn’t for this issue I’d have kept using the mini pill but I couldn’t deal with it anymore as it was preventing me from living my life normally


Somewhat positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  5th Jul 25

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
21 years old
🇬🇧 UK
  •  26th Jun 25

Desogestrel pill  

The first 3-5 months were a bit rough, having sex would cause me to get a period and sometimes was painful. I also was definitely more emotional than before. It all calms down over time, I’ve been on it for almost 3 years now and it was the best decision i get very occasionally spotting and cramps if i miss a pill or two but overall I like it


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  24th Jun 25

Desogestrel pill  

I was on Microgynon 30 for almost 8 years and I never had any issues! I changed 3 months ago to the progesterone only pill (Desogesterel) due to my friend getting a blood clot from microgynon, and within a month I began getting spots all over my jawline! I have now had constant spots for 2 months. I also have breakthrough bleeding which I never had on Microgynon. I will be heading back to the pharmacy to discuss my options


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
43 years old
🇬🇧 UK
  •  6th Jun 25

Desogestrel pill  

I’m very satisfied with the pill. I only been taking it for few weeks but my mental health improved so much ! I can’t actually believe it. I used to suffer mood swings due to hormonal fluctuations . None of this is happening . Very happy. No side effects either


Very positive mood

1 more effect

0 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Desomono pill with other contraceptives

Compare the Desogestrel pill with other contraceptives

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