Desogestrel pill vs Cerelle pill

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Desogestrel pill

£From £0.20/day

Cerelle pill

£From £0.20/day

Overview

Rated 2.6

363 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.8

308 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen


Cerelle pill ingredients

Main hormones in Cerelle pill

Less-Androgenic progestogen

What Lowdown reviewers say

34% somewhat negative

43% stopped periods

54% lost sex drive

43% no impact

45% no impact on skin

Cycle return

40% don’t know impact

29% somewhat negative

54% stopped periods

49% lost sex drive

39% gained weight

44% no impact on skin

Cycle return

36% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

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£From £0.20/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Desogestrel pill reviews

363 reviews

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  4th Nov 24

Desogestrel pill  

I started the POP because I had a few migraines with auras on the combined pill and had to stop this. When I started the mini-pill my periods became very irregular. However, I went on the combined pill in the first place because of my irregular cycle so this may just be me. I have noticed my periods are lighter but I never had heavy periods anyway. I have had a few cases of spotting for 2-3weeks after getting my period but this hopefully seems to have settled now after 5/6 months and I get a 3-5 day light period. My skin flared up with bad hormonal acne about 3/4months after I started taking the POP and hasn’t gotten any better. Another reason why I went on the combined pill initially was to help with acne so I feel this has regressed since starting the mini-pill. Also, I have had some horrific cramping at random times. A couple of times has been a whole week of painful cramps but again this hopefully seems to have settled down a bit after about 7/8 months of taking the POP. Overall, I’m not happy with the side effects I’m experiencing, especially my skin, and am considering trying the hormonal coil, but will give it a full year on the POP to see if my body starts to settle.

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Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  31st Oct 24

Desogestrel pill  

I really wanted to like Desogestrel. Initially, my skin was the worst - so oily and immediately broke out in painful acne. This quickly subsided after about 2 weeks. For 3 months, my breasts were so enlarged and sore all the time. I noticed around the 3 month mark that I was experiencing vaginal dryness too. My periods have been totally irregular - since starting Desogestrel in May I've had 10 periods. Many of these were trigged by intercourse. The volume of blood and the level of pain was variable for every period, making it hard to predict. The final straw for me was I started losing my hair around the 5-6 month mark. My hair is noticeably thinner on top and the ends are ruined / look awful. The only positive for me has been that it made me more energetic and have a better / more even mood. It did has not affected my sex drive and I gained a negligible amount of weight.


Somewhat positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  20th Oct 24

Desogestrel pill  

I was prescribed generic Desogestrel mini pill to treat my adenomyosis. I was only on it for a couple of weeks, but I couldn't cope with the symptoms. Daily bleeding and bloating but more worryingly, horrendous nausea, dizziness and migraines. Also had swollen tender enlarged breasts.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  4th Nov 24

Desogestrel pill  

I started the POP because I had a few migraines with auras on the combined pill and had to stop this. When I started the mini-pill my periods became very irregular. However, I went on the combined pill in the first place because of my irregular cycle so this may just be me. I have noticed my periods are lighter but I never had heavy periods anyway. I have had a few cases of spotting for 2-3weeks after getting my period but this hopefully seems to have settled now after 5/6 months and I get a 3-5 day light period. My skin flared up with bad hormonal acne about 3/4months after I started taking the POP and hasn’t gotten any better. Another reason why I went on the combined pill initially was to help with acne so I feel this has regressed since starting the mini-pill. Also, I have had some horrific cramping at random times. A couple of times has been a whole week of painful cramps but again this hopefully seems to have settled down a bit after about 7/8 months of taking the POP. Overall, I’m not happy with the side effects I’m experiencing, especially my skin, and am considering trying the hormonal coil, but will give it a full year on the POP to see if my body starts to settle.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  31st Oct 24

Desogestrel pill  

I really wanted to like Desogestrel. Initially, my skin was the worst - so oily and immediately broke out in painful acne. This quickly subsided after about 2 weeks. For 3 months, my breasts were so enlarged and sore all the time. I noticed around the 3 month mark that I was experiencing vaginal dryness too. My periods have been totally irregular - since starting Desogestrel in May I've had 10 periods. Many of these were trigged by intercourse. The volume of blood and the level of pain was variable for every period, making it hard to predict. The final straw for me was I started losing my hair around the 5-6 month mark. My hair is noticeably thinner on top and the ends are ruined / look awful. The only positive for me has been that it made me more energetic and have a better / more even mood. It did has not affected my sex drive and I gained a negligible amount of weight.


Somewhat positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  20th Oct 24

Desogestrel pill  

I was prescribed generic Desogestrel mini pill to treat my adenomyosis. I was only on it for a couple of weeks, but I couldn't cope with the symptoms. Daily bleeding and bloating but more worryingly, horrendous nausea, dizziness and migraines. Also had swollen tender enlarged breasts.


Very negative mood

1 more effect

0 helpful

0 comments


Cerelle pill reviews

308 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
21 years old
🇬🇧 UK
  •  6 days ago

Cerelle pill  

Started taking in April 2024 finished the last pack September 2024. Had spotting for the first couple months in the place of period which was frustrating (spotting for 14days instead of normal 5-7day period flow). Once settled, periods just completely stopped which made me feel slightly uneasy as there’s no indicator of “missed period” for pregnancy sirens to ring. Mood was a strange one, felt slightly mentally exhausted but difficult to tell whether that was life or the pill, but I do remember having PMS type symptoms (emotional, cramps) once a month, almost mimicking a period without the bleeds.


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th Aug 24

Cerelle pill  

I've only been on this pill for two months so there's a chance this may calm down after the full adjustment period, but the side effects have been interesting. Most notably, my cycle has gone from around 35 days to 13 days, and I have been having a period every other week. The first two periods gave me hope because they were significantly lighter - to the point where I was questioning whether or not I should even log it as a period - and painless. However, the next three periods I've had so far have been gradually getting heavier and I'm getting more cramping. It's weird though because, for most of my period it's still quite light, but on around the second or third day, I do have a few hours where it's quite heavy and crampy, then it subsides again and the rest is light. I had spotting between the first three periods but that's stopped now. Other than the annoying cycle changes, I had a constant lingering headache for the first two weeks, I'm getting more acne than usual, and some vaginal dryness before my period. I don't know if this is worth staying on as I'm only on the pill to manage my painful and heavy periods. Current plan is to finish my three months' supply and take it from there.


Somewhat negative mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 8+ yr
Lowdown user
🇬🇧 UK
  •  24th Jun 24

Cerelle pill  

Overall it’s excellent and all positive, no periods at all and steady mood


Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
21 years old
🇬🇧 UK
  •  6 days ago

Cerelle pill  

Started taking in April 2024 finished the last pack September 2024. Had spotting for the first couple months in the place of period which was frustrating (spotting for 14days instead of normal 5-7day period flow). Once settled, periods just completely stopped which made me feel slightly uneasy as there’s no indicator of “missed period” for pregnancy sirens to ring. Mood was a strange one, felt slightly mentally exhausted but difficult to tell whether that was life or the pill, but I do remember having PMS type symptoms (emotional, cramps) once a month, almost mimicking a period without the bleeds.


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th Aug 24

Cerelle pill  

I've only been on this pill for two months so there's a chance this may calm down after the full adjustment period, but the side effects have been interesting. Most notably, my cycle has gone from around 35 days to 13 days, and I have been having a period every other week. The first two periods gave me hope because they were significantly lighter - to the point where I was questioning whether or not I should even log it as a period - and painless. However, the next three periods I've had so far have been gradually getting heavier and I'm getting more cramping. It's weird though because, for most of my period it's still quite light, but on around the second or third day, I do have a few hours where it's quite heavy and crampy, then it subsides again and the rest is light. I had spotting between the first three periods but that's stopped now. Other than the annoying cycle changes, I had a constant lingering headache for the first two weeks, I'm getting more acne than usual, and some vaginal dryness before my period. I don't know if this is worth staying on as I'm only on the pill to manage my painful and heavy periods. Current plan is to finish my three months' supply and take it from there.


Somewhat negative mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 8+ yr
Lowdown user
🇬🇧 UK
  •  24th Jun 24

Cerelle pill  

Overall it’s excellent and all positive, no periods at all and steady mood


Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  14th Jun 24

Cerelle pill  

I'm giving this pill more time because maybe it's just an adjustment. But I've been a bit weepy with sore breasts and spotting every week. Also a really tender feeling in my lower abdomen-especially during sex. Which I hate obviously. So I'm definitely not getting pregnant because I no longer enjoy sex.. so in that respect it is effective. It's getting one more month and then I'm done.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
Lowdown user
🇬🇧 UK
  •  7th May 24

Cerelle pill  

went on this pill due to high blood pressure, and the experience has been very well. my periods skip a month then return lighter. the first month my bleed was longer but lighter, ever since then it has been lighter. my period cramps have reduced massively. few headaches and light sensitivity but has not occurred in a while. acne has be a little bit worse and oily but clears up after a bit. overall has benefited me and libido increased surprisingly 😊


Very positive mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th May 24

Cerelle pill  

I suffer from migraines and was convinced to try this contraption as a way to prevent hormonal fluctuations and therefore prevent them. This pill left me with status migranosus / intractable migraine. It was horrific


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
Lowdown user
🇬🇧 UK
  •  7th May 24

Cerelle pill  

I started on this contraception when I was 16, and am now 21, so in lots of ways it feels difficult to pin any major changes onto it given I would have changed so much in this time anyway. For me, the best thing about it is that it completely stopped my periods for nearly 4 years and then, after experiencing bleeding for the first time in years and seeking advice from the wonderful team at the lowdown, I was able to double my dose so that periods stopped again. I generally have been stable on it which is brilliant, especially after starting on the combined pill and experiencing intense symptoms of nausea and vomiting. I would definitely recommend it based on my experience!


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
Lowdown user
🇬🇧 UK
  •  4th May 24

Cerelle pill  

Was told I could no longer continue my low dose combined pill (Gedarel) at age 43 because I was deemed overweight by a GP (a nurse looked at me in disbelief at this and actually initially extended my prescription to allow me to enjoy my honeymoon. GP now still stubbornly going on my BMI) Blood pressure fluctuates at times too so didn’t want to go through the stress of not knowing at a 3 month check if I’d suddenly be forced to come off it depending who I saw. Started Cerelle in January. First 6 weeks weren’t pleasant. Really sore breasts, spotting mixed in with random heavier bleeds, dryness when not bleeding and bladder irritation. All calmed down (apart from Dryness)- by third strip stopped spotting etc. Then on fourth strip started to bleed for two weeks (light enough to be ok) but by week 3 was bleeding so heavy was leaking through a heavy tampon/pad/period pants and passing clots with no sign of easing up after a full stressful week of this. Stopped taking the pill and bleeding calmed down. It took another 6 days to stop but feel so relieved. A nurse wanted me to switch straight away onto a new mini pill or coil but honestly I feel my body needs a break. Not sure where to go now as already my body feels so much better/libido back/moods balanced. Fed up of hormones!!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
Lowdown user
🇬🇧 UK
  •  26th Apr 24

Cerelle pill  

Short term symptoms were: very tender breasts and feeling weird for a week couple of weeks. Most importantly I suppose - I did not get pregnant while on the mini pill, so it did it's job. It also stopped my periods completely, which was convenient. I was struggling on and off with depression starting just BEFORE I started on the pill, so it didn't caused thay but but I do think it prolonged the problem.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  26th Apr 24

Cerelle pill  

Put on a lot of weight


Improved skin

1 more effect

0 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Desogestrel pill with other contraceptives

Compare the Cerelle pill with other contraceptives

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