Desogestrel pill vs Cerelle pill

Need help choosing? Speak to a doctor
Desogestrel pill

£From £0.20/day

Cerelle pill

£From £0.20/day

Overview

Rated 2.6

375 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.8

312 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen


Cerelle pill ingredients

Main hormones in Cerelle pill

Less-Androgenic progestogen

What Lowdown reviewers say

34% somewhat negative

43% stopped periods

54% lost sex drive

43% no impact

46% no impact on skin

Cycle return

41% don’t know impact

29% somewhat negative

53% stopped periods

49% lost sex drive

39% gained weight

45% no impact on skin

Cycle return

36% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

Try it now

£From £0.20/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Desogestrel pill reviews

375 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
23 years old
🇬🇧 UK
  •  6 days ago

Desogestrel pill  

Did not enjoy this pill! Tried for around 5 months, mood was poor and crying very easily or completely numb! Skin got bad at first but then was okay! Gained weight around increase by a dress size or two, felt bloated constantly and breast size increased but sore! Vaginal dryness was extreme was even sore to walk and have thrush twice in this 5 month period! Was spotting pretty much constantly and obviously unable to track periods with it being a continuous pill and they were irregular.

Read more

Very negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
19 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I got put on this pill when i had a miscarriage, i get worried from time to time about my period. I have the flo app and i’m on my period about every 2 weeks, but it’s not exactly a period it’s just very very light and lasts for longer then a period should last this only started happening when i missed a pill for a day and the next day took 2 of them so it didn’t screw the pill up in my body and it has so it worries me. I’ve also put on so much weight using the pill.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
32 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I was 30 when I started this for anyone wanting reference and have had three children. I suffered from horrific period and ovulation pain coupled with ovarian cysts. I had tried many different forms of contraception but I cannot take estrogen as it gives me Hyperemesis Gravidarum, not uncommon in those who have also experienced it in pregnancy, which I did. The first three months weren’t great, mood was all over the place and libido plummeted but after that it levelled out and I’m glad I waited it out. My periods stopped almost immediately and so did my ovulation pain. As I usually got ovarian cysts that burst at the time of ovulation, that’s pretty much stopped too and I’ve gone from having cysts burst monthly, to maybe once or twice a year. It’s dramatically improved my quality of life and I’m so happy on it. What with it being desogestrel, it has a 12 hour time window, so if you forget to take it at your usual time, as long as you take it in the 12 hours following, you’ll still be protected. I’m usually fine as I take it first thing, but it’s always good to know.


Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
23 years old
🇬🇧 UK
  •  6 days ago

Desogestrel pill  

Did not enjoy this pill! Tried for around 5 months, mood was poor and crying very easily or completely numb! Skin got bad at first but then was okay! Gained weight around increase by a dress size or two, felt bloated constantly and breast size increased but sore! Vaginal dryness was extreme was even sore to walk and have thrush twice in this 5 month period! Was spotting pretty much constantly and obviously unable to track periods with it being a continuous pill and they were irregular.


Very negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
19 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I got put on this pill when i had a miscarriage, i get worried from time to time about my period. I have the flo app and i’m on my period about every 2 weeks, but it’s not exactly a period it’s just very very light and lasts for longer then a period should last this only started happening when i missed a pill for a day and the next day took 2 of them so it didn’t screw the pill up in my body and it has so it worries me. I’ve also put on so much weight using the pill.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
32 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I was 30 when I started this for anyone wanting reference and have had three children. I suffered from horrific period and ovulation pain coupled with ovarian cysts. I had tried many different forms of contraception but I cannot take estrogen as it gives me Hyperemesis Gravidarum, not uncommon in those who have also experienced it in pregnancy, which I did. The first three months weren’t great, mood was all over the place and libido plummeted but after that it levelled out and I’m glad I waited it out. My periods stopped almost immediately and so did my ovulation pain. As I usually got ovarian cysts that burst at the time of ovulation, that’s pretty much stopped too and I’ve gone from having cysts burst monthly, to maybe once or twice a year. It’s dramatically improved my quality of life and I’m so happy on it. What with it being desogestrel, it has a 12 hour time window, so if you forget to take it at your usual time, as long as you take it in the 12 hours following, you’ll still be protected. I’m usually fine as I take it first thing, but it’s always good to know.


Very positive mood

0 helpful

0 comments


Cerelle pill reviews

312 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
28 years old
🇬🇧 UK
  •  2 weeks ago

Cerelle pill  

I had an unpleasant experience using Cerelle. It was the first birth control I tried and wasn't given any other options or choice by the GP at the time. I had a 2month long heavy and painful period, worsened skin, hair loss, severe backne to name a few side effects. Really bad experience for me sadly. Having now tried over 10 other birth control pills- mini and combined, I learned that I am very sensitive to progesterone so the mini pill just isn't for me sadly. I'm now on the Patch and loving it.


Worse skin

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
35 years old
🇬🇧 UK
  •  3 weeks ago

Cerelle pill  

I took this for endometriosis, but not worth it because of facial hair growth. I had breakthrough bleeding every 4-6 months for about 4-5 days, fairly light and not too painful. My sex drive and weight were unaffected, however I got thick dark hair on my stomach, inner thighs, chest and face. This destroyed my self esteem so my mood was obviously low. After stopping the hair did not revert back which is common so I had electrolysis which took care of it. Then 2 years later I went back on this pill stupidly to try and help the endometriosis, the hair came back within 2 months. I have since stopped this pill, spent even more money on electrolysis and have had no issues after regarding that. It took about 3-5 months for my cycle to regulate after coming off birth control. I’m thinking about trying slynd as it is supposed to be anti androgenise, we’ll see.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
42 years old
🇬🇧 UK
  •  3 weeks ago

Cerelle pill  

I used this for 6 months hoping my body would adjust but had to stop. My periods became really irregular, and super heavy. The first month, I had 2 periods (both lasted around 10-12 days), second month I got one period, 3rd month I got nothing, and then months 4 - 6 I had 3 periods in 7 weeks, all lasting around 12 days and far heavier than my normal periods. I felt like I had backache most of those last couple of months as that's something that happens whenever I'm menstruating. I've tried other pills and never had side effects like this, so I've stopped these now and will go back to another type of pill.


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
28 years old
🇬🇧 UK
  •  2 weeks ago

Cerelle pill  

I had an unpleasant experience using Cerelle. It was the first birth control I tried and wasn't given any other options or choice by the GP at the time. I had a 2month long heavy and painful period, worsened skin, hair loss, severe backne to name a few side effects. Really bad experience for me sadly. Having now tried over 10 other birth control pills- mini and combined, I learned that I am very sensitive to progesterone so the mini pill just isn't for me sadly. I'm now on the Patch and loving it.


Worse skin

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
35 years old
🇬🇧 UK
  •  3 weeks ago

Cerelle pill  

I took this for endometriosis, but not worth it because of facial hair growth. I had breakthrough bleeding every 4-6 months for about 4-5 days, fairly light and not too painful. My sex drive and weight were unaffected, however I got thick dark hair on my stomach, inner thighs, chest and face. This destroyed my self esteem so my mood was obviously low. After stopping the hair did not revert back which is common so I had electrolysis which took care of it. Then 2 years later I went back on this pill stupidly to try and help the endometriosis, the hair came back within 2 months. I have since stopped this pill, spent even more money on electrolysis and have had no issues after regarding that. It took about 3-5 months for my cycle to regulate after coming off birth control. I’m thinking about trying slynd as it is supposed to be anti androgenise, we’ll see.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
42 years old
🇬🇧 UK
  •  3 weeks ago

Cerelle pill  

I used this for 6 months hoping my body would adjust but had to stop. My periods became really irregular, and super heavy. The first month, I had 2 periods (both lasted around 10-12 days), second month I got one period, 3rd month I got nothing, and then months 4 - 6 I had 3 periods in 7 weeks, all lasting around 12 days and far heavier than my normal periods. I felt like I had backache most of those last couple of months as that's something that happens whenever I'm menstruating. I've tried other pills and never had side effects like this, so I've stopped these now and will go back to another type of pill.


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
24 years old
🇬🇧 UK
  •  1 month ago

Cerelle pill  

Had some mood issues during the first 3 months such a depression, low moods, emotional but put that down to my body adjusting. But after 5/6 months all the side effects of depression, low mood, constant crying can back much worse. Had 6 week period cycles with irregular bleeding and spotting and heavy cramping. Had to come off the pills as they were affecting my life so greatly.


Very negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
21 years old
🇬🇧 UK
  •  15th Dec 24

Cerelle pill  

Started taking in April 2024 finished the last pack September 2024. Had spotting for the first couple months in the place of period which was frustrating (spotting for 14days instead of normal 5-7day period flow). Once settled, periods just completely stopped which made me feel slightly uneasy as there’s no indicator of “missed period” for pregnancy sirens to ring. Mood was a strange one, felt slightly mentally exhausted but difficult to tell whether that was life or the pill, but I do remember having PMS type symptoms (emotional, cramps) once a month, almost mimicking a period without the bleeds.


Worse skin

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th Aug 24

Cerelle pill  

I've only been on this pill for two months so there's a chance this may calm down after the full adjustment period, but the side effects have been interesting. Most notably, my cycle has gone from around 35 days to 13 days, and I have been having a period every other week. The first two periods gave me hope because they were significantly lighter - to the point where I was questioning whether or not I should even log it as a period - and painless. However, the next three periods I've had so far have been gradually getting heavier and I'm getting more cramping. It's weird though because, for most of my period it's still quite light, but on around the second or third day, I do have a few hours where it's quite heavy and crampy, then it subsides again and the rest is light. I had spotting between the first three periods but that's stopped now. Other than the annoying cycle changes, I had a constant lingering headache for the first two weeks, I'm getting more acne than usual, and some vaginal dryness before my period. I don't know if this is worth staying on as I'm only on the pill to manage my painful and heavy periods. Current plan is to finish my three months' supply and take it from there.


Somewhat negative mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 8+ yr
Lowdown user
🇬🇧 UK
  •  24th Jun 24

Cerelle pill  

Overall it’s excellent and all positive, no periods at all and steady mood


Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  14th Jun 24

Cerelle pill  

I'm giving this pill more time because maybe it's just an adjustment. But I've been a bit weepy with sore breasts and spotting every week. Also a really tender feeling in my lower abdomen-especially during sex. Which I hate obviously. So I'm definitely not getting pregnant because I no longer enjoy sex.. so in that respect it is effective. It's getting one more month and then I'm done.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
Lowdown user
🇬🇧 UK
  •  7th May 24

Cerelle pill  

went on this pill due to high blood pressure, and the experience has been very well. my periods skip a month then return lighter. the first month my bleed was longer but lighter, ever since then it has been lighter. my period cramps have reduced massively. few headaches and light sensitivity but has not occurred in a while. acne has be a little bit worse and oily but clears up after a bit. overall has benefited me and libido increased surprisingly 😊


Very positive mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th May 24

Cerelle pill  

I suffer from migraines and was convinced to try this contraption as a way to prevent hormonal fluctuations and therefore prevent them. This pill left me with status migranosus / intractable migraine. It was horrific


Somewhat negative mood

1 more effect

0 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Desogestrel pill with other contraceptives

Compare the Cerelle pill with other contraceptives

Order online

Order online now

Use our online prescription in under 5 mins

  • No GP appointment needed

  • Free standard delivery

Speak to a doctor

Not sure yet? Speak to a doctor

Schedule an appointment now

87% of women are happier with their contraceptive choice after speaking with one of The Lowdown's doctors

The Lowdown Footer

Women's health, reviewed.

Get the best women’s health info in your inbox

You are signing up to receive The Lowdown's latest findings and news in women's health. Your data will be used in accordance with our Privacy & Cookie policy

Built by doctors and experts

Our tools are made by medical professionals for your peace of mind

Our website uses affiliate links and we may earn a small commission if you click on them