Cerelle pill vs Desogestrel pill

Need help choosing? Speak to a doctor
Cerelle pill

£From £0.20/day

Desogestrel pill

£From £0.20/day

Overview

Rated 2.8

308 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.6

363 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Cerelle pill ingredients

Main hormones in Cerelle pill

Less-Androgenic progestogen


Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen

What Lowdown reviewers say

29% somewhat negative

54% stopped periods

49% lost sex drive

39% gained weight

44% no impact on skin

Cycle return

36% don’t know impact

34% somewhat negative

43% stopped periods

54% lost sex drive

43% no impact

45% no impact on skin

Cycle return

40% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

Try it now

£From £0.20/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Cerelle pill reviews

308 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
21 years old
🇬🇧 UK
  •  6 days ago

Cerelle pill  

Started taking in April 2024 finished the last pack September 2024. Had spotting for the first couple months in the place of period which was frustrating (spotting for 14days instead of normal 5-7day period flow). Once settled, periods just completely stopped which made me feel slightly uneasy as there’s no indicator of “missed period” for pregnancy sirens to ring. Mood was a strange one, felt slightly mentally exhausted but difficult to tell whether that was life or the pill, but I do remember having PMS type symptoms (emotional, cramps) once a month, almost mimicking a period without the bleeds.

Read more

Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th Aug 24

Cerelle pill  

I've only been on this pill for two months so there's a chance this may calm down after the full adjustment period, but the side effects have been interesting. Most notably, my cycle has gone from around 35 days to 13 days, and I have been having a period every other week. The first two periods gave me hope because they were significantly lighter - to the point where I was questioning whether or not I should even log it as a period - and painless. However, the next three periods I've had so far have been gradually getting heavier and I'm getting more cramping. It's weird though because, for most of my period it's still quite light, but on around the second or third day, I do have a few hours where it's quite heavy and crampy, then it subsides again and the rest is light. I had spotting between the first three periods but that's stopped now. Other than the annoying cycle changes, I had a constant lingering headache for the first two weeks, I'm getting more acne than usual, and some vaginal dryness before my period. I don't know if this is worth staying on as I'm only on the pill to manage my painful and heavy periods. Current plan is to finish my three months' supply and take it from there.


Somewhat negative mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 8+ yr
Lowdown user
🇬🇧 UK
  •  24th Jun 24

Cerelle pill  

Overall it’s excellent and all positive, no periods at all and steady mood


Very positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
21 years old
🇬🇧 UK
  •  6 days ago

Cerelle pill  

Started taking in April 2024 finished the last pack September 2024. Had spotting for the first couple months in the place of period which was frustrating (spotting for 14days instead of normal 5-7day period flow). Once settled, periods just completely stopped which made me feel slightly uneasy as there’s no indicator of “missed period” for pregnancy sirens to ring. Mood was a strange one, felt slightly mentally exhausted but difficult to tell whether that was life or the pill, but I do remember having PMS type symptoms (emotional, cramps) once a month, almost mimicking a period without the bleeds.


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  7th Aug 24

Cerelle pill  

I've only been on this pill for two months so there's a chance this may calm down after the full adjustment period, but the side effects have been interesting. Most notably, my cycle has gone from around 35 days to 13 days, and I have been having a period every other week. The first two periods gave me hope because they were significantly lighter - to the point where I was questioning whether or not I should even log it as a period - and painless. However, the next three periods I've had so far have been gradually getting heavier and I'm getting more cramping. It's weird though because, for most of my period it's still quite light, but on around the second or third day, I do have a few hours where it's quite heavy and crampy, then it subsides again and the rest is light. I had spotting between the first three periods but that's stopped now. Other than the annoying cycle changes, I had a constant lingering headache for the first two weeks, I'm getting more acne than usual, and some vaginal dryness before my period. I don't know if this is worth staying on as I'm only on the pill to manage my painful and heavy periods. Current plan is to finish my three months' supply and take it from there.


Somewhat negative mood

1 more effect

1 helpful

0 comments

Progestogen-only / Mini pill  
Used for 8+ yr
Lowdown user
🇬🇧 UK
  •  24th Jun 24

Cerelle pill  

Overall it’s excellent and all positive, no periods at all and steady mood


Very positive mood

0 helpful

0 comments


Desogestrel pill reviews

363 reviews

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  4th Nov 24

Desogestrel pill  

I started the POP because I had a few migraines with auras on the combined pill and had to stop this. When I started the mini-pill my periods became very irregular. However, I went on the combined pill in the first place because of my irregular cycle so this may just be me. I have noticed my periods are lighter but I never had heavy periods anyway. I have had a few cases of spotting for 2-3weeks after getting my period but this hopefully seems to have settled now after 5/6 months and I get a 3-5 day light period. My skin flared up with bad hormonal acne about 3/4months after I started taking the POP and hasn’t gotten any better. Another reason why I went on the combined pill initially was to help with acne so I feel this has regressed since starting the mini-pill. Also, I have had some horrific cramping at random times. A couple of times has been a whole week of painful cramps but again this hopefully seems to have settled down a bit after about 7/8 months of taking the POP. Overall, I’m not happy with the side effects I’m experiencing, especially my skin, and am considering trying the hormonal coil, but will give it a full year on the POP to see if my body starts to settle.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  31st Oct 24

Desogestrel pill  

I really wanted to like Desogestrel. Initially, my skin was the worst - so oily and immediately broke out in painful acne. This quickly subsided after about 2 weeks. For 3 months, my breasts were so enlarged and sore all the time. I noticed around the 3 month mark that I was experiencing vaginal dryness too. My periods have been totally irregular - since starting Desogestrel in May I've had 10 periods. Many of these were trigged by intercourse. The volume of blood and the level of pain was variable for every period, making it hard to predict. The final straw for me was I started losing my hair around the 5-6 month mark. My hair is noticeably thinner on top and the ends are ruined / look awful. The only positive for me has been that it made me more energetic and have a better / more even mood. It did has not affected my sex drive and I gained a negligible amount of weight.


Somewhat positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  20th Oct 24

Desogestrel pill  

I was prescribed generic Desogestrel mini pill to treat my adenomyosis. I was only on it for a couple of weeks, but I couldn't cope with the symptoms. Daily bleeding and bloating but more worryingly, horrendous nausea, dizziness and migraines. Also had swollen tender enlarged breasts.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  4th Nov 24

Desogestrel pill  

I started the POP because I had a few migraines with auras on the combined pill and had to stop this. When I started the mini-pill my periods became very irregular. However, I went on the combined pill in the first place because of my irregular cycle so this may just be me. I have noticed my periods are lighter but I never had heavy periods anyway. I have had a few cases of spotting for 2-3weeks after getting my period but this hopefully seems to have settled now after 5/6 months and I get a 3-5 day light period. My skin flared up with bad hormonal acne about 3/4months after I started taking the POP and hasn’t gotten any better. Another reason why I went on the combined pill initially was to help with acne so I feel this has regressed since starting the mini-pill. Also, I have had some horrific cramping at random times. A couple of times has been a whole week of painful cramps but again this hopefully seems to have settled down a bit after about 7/8 months of taking the POP. Overall, I’m not happy with the side effects I’m experiencing, especially my skin, and am considering trying the hormonal coil, but will give it a full year on the POP to see if my body starts to settle.


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  31st Oct 24

Desogestrel pill  

I really wanted to like Desogestrel. Initially, my skin was the worst - so oily and immediately broke out in painful acne. This quickly subsided after about 2 weeks. For 3 months, my breasts were so enlarged and sore all the time. I noticed around the 3 month mark that I was experiencing vaginal dryness too. My periods have been totally irregular - since starting Desogestrel in May I've had 10 periods. Many of these were trigged by intercourse. The volume of blood and the level of pain was variable for every period, making it hard to predict. The final straw for me was I started losing my hair around the 5-6 month mark. My hair is noticeably thinner on top and the ends are ruined / look awful. The only positive for me has been that it made me more energetic and have a better / more even mood. It did has not affected my sex drive and I gained a negligible amount of weight.


Somewhat positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  20th Oct 24

Desogestrel pill  

I was prescribed generic Desogestrel mini pill to treat my adenomyosis. I was only on it for a couple of weeks, but I couldn't cope with the symptoms. Daily bleeding and bloating but more worryingly, horrendous nausea, dizziness and migraines. Also had swollen tender enlarged breasts.


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  14th Oct 24

Desogestrel pill  

This desogestrol progesterone only pill was recommended to me during a specialist appointment for severe Menorrhagia, I also have endometriosis. On the first day of taking I did not notice any symptoms, on the second day my whole abdomen from side to side became painful, tender and swollen, same on day three and four progressively becoming worse. On day three and four I was getting pins and needles in both my hands intermittently. I felt nauseous on day two, three and four (this became constant from day three to four) and had some dizzy spells on both days too. I also experienced tender breasts from day 1 to 4. I exercise well everyday and noticed I was sweating more than usual and breathless after exertion, a lot more than usual. My sex drive changed because of the side effects I think. I stopped taking this medication after the fourth tablet because the side effects were so bad.


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
Lowdown user
🇬🇧 UK
  •  10th Oct 24

Desogestrel pill  

Was put on this to help with my severe period pains. It has helped but I'm not sure it's worth it with the side effects. I can honestly say I am depressed. I have zero motivation, zero energy, zero inclination to do anything I used to enjoy. My sex drive has disappeared it doesn't matter because I've bled for the majority of the time I've been taking it. I want to stop but my GP won't try me on anything else until I've been on this for 3 months.


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
Lowdown user
🇬🇧 UK
  •  9th Oct 24

Desogestrel pill  

I have been taking Desogestral for just over 6 months. It took 3-4 months of irregular bleeding/spotting before my periods seem to have stopped completely. I do notice that I have had several occurrences of thrush along with weight gain/increased hunger, tender breasts and occasional period like cramping without bleeding. Mood overall has been slightly lower and feel like I am prone to pms symptoms still (teary, low mood) at the time I would have previously been due on. Had been off contraception for several years as combined pill previously contributed to anxiety/depression. Wanted something to control v heavy periods and not impact mood greatly and this seems to be working so far despite some unwanted side effects


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
Lowdown user
🇬🇧 UK
  •  8th Oct 24

Desogestrel pill  

Awful , periods went on for 16-28 days over 3 months. Decided to stop taking this totally as it was awful. Don’t recommend at all.


Very negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
Lowdown user
🇬🇧 UK
  •  25th Sep 24

Desogestrel pill  

I started taking the minipill about 6 months ago because of my really heavy and painful periods. And the first three months I still had my period, but it did get a lot lighter and less painful. The last 3 months I've had no period except for a week of spotting. My mood has become more stable, I used to become almost depressed before my period. I do however become nauseaus a lot faster especially if I'm stressed, I have lost 5 kg almost because of that. I don't think this is the best contraceptive, but I do like that it only contains one type of hormone and that I don't have my period anymore. But I'm not planning on taking it for a very long time.


Somewhat positive mood

1 more effect

0 helpful

1 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
Lowdown user
🇬🇧 UK
  •  13th Aug 24

Desogestrel pill  

Started this pill as I had horrendous migraines on Rigevidon. Was excited to start the mini pill and to not have bleeds in between pills but was I wrong. The first 5 months I’ve had random bleeding- which I expected (but not for over a week straight) I’ve also been heavily dizzy, nauseous and have had 0 sex drive which has affected my relationship heavily.


Somewhat negative mood

3 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 8+ yr
Lowdown user
🇬🇧 UK
  •  6th Aug 24

Desogestrel pill  

Hugely helped with period pains (no periods!). Has evened out any emotional changes - I feel very stable. No nausea like with the combined pill. Lost weight (as well as boob!) but unsure if that's compared to when I was on combined pill or baseline.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Cerelle pill with other contraceptives

Compare the Desogestrel pill with other contraceptives

Order online

Order online now

Use our online prescription in under 5 mins

  • No GP appointment needed

  • Free standard delivery

Speak to a doctor

Not sure yet? Speak to a doctor

Schedule an appointment now

87% of women are happier with their contraceptive choice after speaking with one of The Lowdown's doctors

The Lowdown Footer

Women's health, reviewed.

Get the best women’s health info in your inbox

You are signing up to receive The Lowdown's latest findings and news in women's health. Your data will be used in accordance with our Privacy & Cookie policy

Built by doctors and experts

Our tools are made by medical professionals for your peace of mind

Our website uses affiliate links and we may earn a small commission if you click on them