Cerazette pill vs Desogestrel pill

Need help choosing? Speak to a doctor
Cerazette pill

£From £0.24/day

Desogestrel pill

£From £0.20/day

Overview

Rated 2.6

412 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.7

398 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Cerazette pill ingredients

Main hormones in Cerazette pill

Less-Androgenic progestogen


Desogestrel pill ingredients

Main hormones in Desogestrel pill

Less-Androgenic progestogen

What Lowdown reviewers say

32% somewhat negative

52% stopped periods

54% lost sex drive

45% no impact

38% no impact on skin

Cycle return

34% don’t know impact

33% somewhat negative

43% stopped periods

53% lost sex drive

44% no impact

47% no impact on skin

Cycle return

41% don’t know impact

Benefits: What this contraceptive can help with

Period pain

Period pain

Try it now

£From £0.24/day

Try it now

£From £0.20/day

Check out our latest reviews

Real life reviews from people like you

Cerazette pill reviews

412 reviews

Progestogen-only / Mini pill  
Used for 1 - 3 mo
35 years old
🇬🇧 UK
  •  28th Jun 25

Cerazette pill  

I really wanted to write about my positive experience as most people write reviews when they have a negative experience, for me the Cerazette has been really good, it improved my feeling of being in balance and lessened mood swings, it did not effect my libido, in fact in the beginning I noticed a higher libido, but most importantly I suffer from migraines with aura and since I started taking this a month ago I didn’t have an intense migraine, just one or two mild days and I normally have 2/3 days per week so in a month 8 at least. The only negative things are not too bad: I have very tender breasts which became a bit bigger but I heard this might go away after 3 months or so and I got a little bit of acne but nothing too crazy and this also usually settles after taking it consistently for a few month. All in all for me it’s truly been life changing.

Read more

Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
25 years old
🇬🇧 UK
  •  6th Jun 25

Cerazette pill  

I swapped from the combined pill to Cerazette because I was having anxiety, dizziness and low libido. These have both improved since changing. The most annoying thing has been inconsistent bleeding and spotting. I won’t bleed for 3 months then will have spotting out of nowhere for 3 weeks. I have also got acne on my chin which I didn’t have before. Overall though these extra inconveniences have far outweighed the reduced anxiety, dizziness and libido issues.


Very positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
17 years old
🇬🇧 UK
  •  18th May 25

Cerazette pill  

Positive


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
35 years old
🇬🇧 UK
  •  28th Jun 25

Cerazette pill  

I really wanted to write about my positive experience as most people write reviews when they have a negative experience, for me the Cerazette has been really good, it improved my feeling of being in balance and lessened mood swings, it did not effect my libido, in fact in the beginning I noticed a higher libido, but most importantly I suffer from migraines with aura and since I started taking this a month ago I didn’t have an intense migraine, just one or two mild days and I normally have 2/3 days per week so in a month 8 at least. The only negative things are not too bad: I have very tender breasts which became a bit bigger but I heard this might go away after 3 months or so and I got a little bit of acne but nothing too crazy and this also usually settles after taking it consistently for a few month. All in all for me it’s truly been life changing.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
25 years old
🇬🇧 UK
  •  6th Jun 25

Cerazette pill  

I swapped from the combined pill to Cerazette because I was having anxiety, dizziness and low libido. These have both improved since changing. The most annoying thing has been inconsistent bleeding and spotting. I won’t bleed for 3 months then will have spotting out of nowhere for 3 weeks. I have also got acne on my chin which I didn’t have before. Overall though these extra inconveniences have far outweighed the reduced anxiety, dizziness and libido issues.


Very positive mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
17 years old
🇬🇧 UK
  •  18th May 25

Cerazette pill  

Positive


Somewhat positive mood

1 more effect

0 helpful

0 comments


Desogestrel pill reviews

398 reviews

Progestogen-only / Mini pill  
Used for 3 - 6 mo
20 years old
🇬🇧 UK
  •  3 days ago

Desogestrel pill  

Ok but not a fan of the hair loss and continuous spotting


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1 week ago

Desogestrel pill  

i’m not sure if it is normal but i have been on this pill for 3 months. a week into the taking the pill my period finally came back after around 100 days. since then ive had very irregular periods often bleeding for extended periods of time and also spotting more often with the periods being closer together. i have also experienced much more mood changes as i have felt somewhat more depressed on this pill. this might just be my experience and might also be influenced by the fact i am still going through pubity as i’m 16 yet i still can’t stop thinking that something is wrong .


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
24 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I’m was happy with the mini pill as I took it while breastfeeding my son, however as soon as I weaned him my periods came back but they were all over the place. I bled for nearly 2 weeks straight then it finally stopped, but only for 3 days then it started again. If it wasn’t for this issue I’d have kept using the mini pill but I couldn’t deal with it anymore as it was preventing me from living my life normally


Somewhat positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
20 years old
🇬🇧 UK
  •  3 days ago

Desogestrel pill  

Ok but not a fan of the hair loss and continuous spotting


Top side effects not reported

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
16 years old
🇬🇧 UK
  •  1 week ago

Desogestrel pill  

i’m not sure if it is normal but i have been on this pill for 3 months. a week into the taking the pill my period finally came back after around 100 days. since then ive had very irregular periods often bleeding for extended periods of time and also spotting more often with the periods being closer together. i have also experienced much more mood changes as i have felt somewhat more depressed on this pill. this might just be my experience and might also be influenced by the fact i am still going through pubity as i’m 16 yet i still can’t stop thinking that something is wrong .


Somewhat negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
24 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

I’m was happy with the mini pill as I took it while breastfeeding my son, however as soon as I weaned him my periods came back but they were all over the place. I bled for nearly 2 weeks straight then it finally stopped, but only for 3 days then it started again. If it wasn’t for this issue I’d have kept using the mini pill but I couldn’t deal with it anymore as it was preventing me from living my life normally


Somewhat positive mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
21 years old
🇬🇧 UK
  •  26th Jun 25

Desogestrel pill  

The first 3-5 months were a bit rough, having sex would cause me to get a period and sometimes was painful. I also was definitely more emotional than before. It all calms down over time, I’ve been on it for almost 3 years now and it was the best decision i get very occasionally spotting and cramps if i miss a pill or two but overall I like it


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  24th Jun 25

Desogestrel pill  

I was on Microgynon 30 for almost 8 years and I never had any issues! I changed 3 months ago to the progesterone only pill (Desogesterel) due to my friend getting a blood clot from microgynon, and within a month I began getting spots all over my jawline! I have now had constant spots for 2 months. I also have breakthrough bleeding which I never had on Microgynon. I will be heading back to the pharmacy to discuss my options


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
43 years old
🇬🇧 UK
  •  6th Jun 25

Desogestrel pill  

I’m very satisfied with the pill. I only been taking it for few weeks but my mental health improved so much ! I can’t actually believe it. I used to suffer mood swings due to hormonal fluctuations . None of this is happening . Very happy. No side effects either


Very positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 12 - 18 mo
26 years old
🇬🇧 UK
  •  1st Jun 25

Desogestrel pill  

I was so concerned about weight gain and mood changes but have not experienced this. I have barely any side effects and have had a really positive experience!


Decreased sex drive

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
22 years old
🇬🇧 UK
  •  30th May 25

Desogestrel pill  

I use this pill in combination with a copper coil and it has helped enormously with my PMDD symptoms. I used to really struggle around ovulation with feeling very unwell and now that I don’t have a cycle everything is a lot calmer. I’ve had some spotting and I’m sweating more but it’s much better than having hellish and painful periods. I now don’t have periods at all, which is so much less stressful. I feel like I can finally enjoy my life.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Contraceptive alternatives and comparisons

Compare the Cerazette pill with other contraceptives

Compare the Desogestrel pill with other contraceptives

Order online

Order online now

Use our online prescription in under 5 mins

  • No GP appointment needed

  • Free standard delivery

Speak to a doctor

Not sure yet? Speak to a doctor

Schedule an appointment now

87% of women are happier with their contraceptive choice after speaking with one of The Lowdown's doctors

The Lowdown Footer

Women's health, reviewed.

Get the best women’s health info in your inbox

You are signing up to receive The Lowdown's latest findings and news in women's health. Your data will be used in accordance with our Privacy & Cookie policy

Built by doctors and experts

Our tools are made by medical professionals for your peace of mind

Our website uses affiliate links and we may earn a small commission if you click on them