Side effects

Dretine pill side effects

2.8

16 reviews

What Lowdown reviewers say

Data is taken from self reported Lowdown user reviews

31% very negative

31% stopped periods

38% no impact

50% no impact

44% improved skin

Cycle return

100% don’t know impact

Dretine pill

Dretine pill common side effects

Data is taken from self reported Lowdown user reviews

44% of Dretine pill reviewers reported headaches

38% of Dretine pill reviewers reported breast enlargement

31% of Dretine pill reviewers reported vaginal discharge

31% of Dretine pill reviewers reported vaginal dryness

31% of Dretine pill reviewers reported tender breasts


Data is taken from self reported Lowdown user reviews


Reviews

2.8

16 reviews

Filter reviews

Community reviews

Combined pill  
Used for 18 mo - 3 yr
24 years old
🇬🇧 UK
  •  3 weeks ago

Dretine pill  

I was switched from taking the Yasmin pill to Dretine. I was told they had the exact same hormones. I have polycystic ovaries and Yasmin had been working perfectly for me. The first few months on Dretine were hell. I became severely depressed. Crying every day, anxious and mood swings. This lasted 2-3 months. This did get better. But it shouldn’t be the case that you have to go through this when taking the pill. I’ve taken the pill in different ways to help control pain and breakthrough bleeding but nothing something seems to stop the breakthrough bleeding. It’s always dark brown and clots. I also experienced a major increase in my blood pressure. My skin has been clear and pain levels are low.

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Somewhat negative mood

1 more effect

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
26 years old
🇬🇧 UK
  •  1 month ago

Dretine pill  

This is the worst thing I’ve ever done and I’m not exaggerating. Constantly up and down with my emotions, although mostly down and uncontrollable crying a lot of the time. Had a huge panic attack 2 weeks in, had to call 111 as I thought I was having a heart attack. Made me binge endlessly and uncontrollably. Made my muscles ache and made me more susceptible to injuries, and as a regular gymgoer, it significantly affected my training and fitness and I couldn’t understand why, but the longer I was on it, the worse I felt. Decided to come off after 2 months. Would HIGHLY recommend avoiding this pill. It really? really did not agree with me.


Very negative mood

3 more effects

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
19 years old
🇬🇧 UK
  •  6th Mar 26

Dretine pill  

I went on this pill to sort out mood swings before my period and it absolutely sorted that out. I only took it for about 3 months though, because I had some dizziness and nausea while I was on it at random times which was bearable but not enjoyable so I switched to a different pill. I now take Milinette 20/75 and the lower oestrogen dose (20 vs. 30 with dretine) sorted out the nausea.


Top side effects not reported

0 helpful

0 comments

Combined pill  
Used for 12 - 18 mo
20 years old
🇬🇧 UK
  •  1st Dec 25

Dretine pill  

This has by far been the best pill for me I love how confident and comfortable I feel


Very positive mood

3 more effects

0 helpful

0 comments

Combined pill  
Used for 3 - 5 yr
24 years old
🇬🇧 UK
  •  12th Jul 25

Dretine pill  

My boobs have got so much bigger but my skin it completely cleared my awful awful acne and I have the clearest skin now.


Improved skin

1 more effect

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
43 years old
🇬🇧 UK
  •  18th Jun 25

Dretine pill  

Low mood, caused depression anxiety and lethargy


Very negative mood

0 helpful

0 comments

Combined pill  
Used for 3 - 6 mo
19 years old
🇬🇧 UK
  •  30th Mar 25

Dretine pill  

Cleared my skin up really well after suffering with acne for years. Thought I’d found the perfect pill until it made me feel severely depressed and constant mood swings. I have been taking this pill for 7 months and no improvement on mood just cleared my skin well


Somewhat negative mood

2 more effects

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
21 years old
🇬🇧 UK
  •  23rd Mar 25

Dretine pill  

I was initially prescribed Yasmin to help with low moods/depression before my period. However, I was then switched to Dretine without explanation and told it was the same as Yasmin. Since taking it, my mood has been all over the place- very sensitive, sad, depression-like feelings, anxiety/overthinking a lot more than usual. I'm switching back to Yasmin as I had a positive experience with it in the first place.


Very negative mood

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
21 years old
🇬🇧 UK
  •  7th Feb 25

Dretine pill  

I was initially really scared to start taking Dretine, but now that I’m on my fifth packet, I’m so glad I did. My mild hormonal acne completely cleared up after taking two packets, and since then, my skin has been super clear. I still get the occasional pimple, but it’s rare, small, and not inflamed at all. It’s made such a positive difference, and I feel so much more confident in my skin!


Very positive mood

1 more effect

0 helpful

0 comments

Combined pill  
Used for 1 - 3 mo
21 years old
🇬🇧 UK
  •  14th Jan 25

Dretine pill  

It’s okay. The positive is that my cramps are less. I experienced thrush for the first time in my life. I am more weepy but not depressed. I have acne on my lower face after a few weeks that is starting to clear now and I can see my hair is thinning. I also feel very sleepy on this so I am planning to change.


Somewhat negative mood

1 more effect

0 helpful

0 comments

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