Norgestimate is a third-generation synthetic progestin used exclusively in the combined pill along with ethinyl estradiol, a synthetic oestrogen. While it’s rarely seen without its partner in crime, it is used alone as a hormone therapy for menopausal women in some countries.
How does it work?
Norgestimate in combination with oestrogen in the combined pill works by stopping ovulation and thinning the lining of the womb so a fertilised egg can’t implant into it.1 Progestins in combined contraceptive pills can also make your cervical fluid thicker, stopping sperm from being able to enter your uterus.
What is it used in?
Is it androgenic?
Yes, weakly. (Check out our ‘Androgens’ blog for more info on what this means).
What are the side effects?
As norgestimate is almost always taken with ethinyl estradiol in the combined pill, it’s virtually impossible to say which side effects it may cause on its own. The following side effects are common with the combined pill 2:
- Breast tenderness or enlargement
- Mood changes