I've been on this pill for over a year now. The main disadvantage for me was the discharge that came along with Desogestrel. It's more frequent and a different texture, which threw me off as I thought it may be an infection but after going the doctors and getting the all clear, the pill was the only explanation for it. I originally went on it to help with cramps, however I found them to be even worse being on the pill. I still get periods, but they tend to be quite irregular. I noticed it did make me more anxious.